Respiratory infections represent a major global health problem. They are often treated by
parenteral administrations of antimicrobials. Unfortunately, systemic therapies of high-dose …

Multidrug-resistant, Gram-negative infection is a major global determinant of morbidity,
mortality and cost of care. The advent of nanomedicine has enabled tailored engineering of …

Enhancement strategies are necessary to improve the dermal/transdermal bioavailability of
drugs applied to the skin due to its amazing barrier, the stratum corneum. Strategies to …

The characterization of encapsulation efficiency and in vitro drug release from nanoparticle-
based formulations often requires the separation of nanoparticles from unencapsulated …

Paeonol shows effective anti-allergic, anti-inflammatory and analgesic activities. However,
because of its poor solubility in water and high volatility at room temperature, the application …

Pathogens resistant to most conventional anti-infectives are a harbinger of the need to
discover and develop novel anti-infective agents and strategies. Endogenous host defense …

Bacterial invasion into eukaryotic cells and the establishment of intracellular infection has
proven to be an effective means of resisting antibiotic action, as anti‐infective agents …

Colistin (polymixin E) is an antibiotic prescribed with resurging frequency for multidrug
resistant gram negative bacterial infections. It is associated with nephrotoxicity in humans in …

Nano-liposomes are the newly developed delivery systems for cancer therapy that are
finding a position particularly suitable as peptide and protein carriers. These are three …

Luliconazole (LCZ) is a novel topical imidazole medication with broad-spectrum antifungal
activity. Unfortunately, the high potential of LCZ for topical antifungal activity is hampered by …