Structure and function of microbial α-l-fucosidases: a mini review

H Wu, CD Owen, N Juge - Essays in Biochemistry, 2023 - portlandpress.com
Fucose is a monosaccharide commonly found in mammalian, insect, microbial and plant
glycans. The removal of terminal α-l-fucosyl residues from oligosaccharides and …

Employment of fucosidases for the synthesis of fucosylated oligosaccharides with biological potential

F Guzmán‐Rodríguez… - Biotechnology and …, 2019 - Wiley Online Library
Fucosylated oligosaccharides play important physiological roles in humans, including in the
immune response, transduction of signals, early embryogenesis and development, growth …

Biochemical characterization of a novel α-L-fucosidase from Pedobacter sp. and its application in synthesis of 3′-fucosyllactose and 2′-fucosyllactose

R Shi, J Ma, Q Yan, S Yang, Z Fan, Z Jiang - Applied Microbiology and …, 2020 - Springer
Fucosyllactoses have gained much attention owing to their multiple functions, including
prebiotic, immune, gut, and cognition benefits. In this study, human milk oligosaccharide …

The gastrointestinal pathogen Campylobacter jejuni metabolizes sugars with potential help from commensal Bacteroides vulgatus

JM Garber, H Nothaft, B Pluvinage, M Stahl… - Communications …, 2020 - nature.com
Although the gastrointestinal pathogen Campylobacter jejuni was considered
asaccharolytic,> 50% of sequenced isolates possess an operon for l-fucose utilization. In C …

Exploring the sequence-function space of microbial fucosidases

A Martínez Gascueña, H Wu, R Wang… - Communications …, 2024 - nature.com
Microbial α-l-fucosidases catalyse the hydrolysis of terminal α-l-fucosidic linkages and can
perform transglycosylation reactions. Based on sequence identity, α-l-fucosidases are …

Genome-based analysis for the bioactive potential of Streptomyces yeochonensis CN732, an acidophilic filamentous soil actinobacterium

A Malik, YR Kim, IH Jang, S Hwang, DC Oh, SB Kim - BMC genomics, 2020 - Springer
Background Acidophilic members of the genus Streptomyces can be a good source for
novel secondary metabolites and degradative enzymes of biopolymers. In this study, a …

Comparison of anti-pathogenic activities of the human and bovine milk N-glycome: Fucosylation is a key factor

WL Wang, W Wang, YM Du, H Wu, XB Yu, KP Ye, CB Li… - Food Chemistry, 2017 - Elsevier
Health differences between breast-and formula-fed infants have long been apparent despite
great efforts in improving the function of baby formula by adjusting the levels of various milk …

Screening and characterization of an α-L-fucosidase from Bacteroides fragilis NCTC9343 for synthesis of fucosyl-N-acetylglucosamine disaccharides

P Liu, H Zhang, Y Wang, X Chen, L **, L Xu… - Applied Microbiology and …, 2020 - Springer
Fucosyl-N-acetylglucosamine disaccharides are present in many biologically important
oligosaccharides, such as human milk oligosaccharides, Lewis carbohydrate antigens, and …

Synthesis of 2′-fucosyllactose from apple pomace–derived xyloglucan oligosaccharides by an α-L-fucosidase from Pedobacter sp. CAU209

R Shi, S Yang, N Wang, Q Yan, X Yan… - Applied Microbiology and …, 2023 - Springer
Fucosyllactose (2′-FL) is known for its ability to provide various health benefits to infants,
such as gut maturation, pathogen resistance, improved immunity, and nervous system …

Characterization of a new α-l-fucosidase isolated from Fusarium proliferatum LE1 that is regioselective to α-(1→ 4)-l-fucosidic linkage in the hydrolysis of α-l …

SV Shvetsova, KA Shabalin, KS Bobrov, DR Ivanen… - Biochimie, 2017 - Elsevier
Here, we report the biochemical characterization of a novel α-l-fucosidase with broad
substrate specificity (FpFucA) isolated from the mycelial fungus Fusarium proliferatum LE1 …