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Inflammatory bowel diseases (IBD) represent a growing public health concern due to
increasing incidence worldwide. The current notion on the pathogenesis of IBD is that …

Tumor necrosis factor α (TNFα) is a potent inflammatory cytokine. In human, the TNFα gene
is located within the highly polymorphic major histocompatibility complex (MHC) region on …

Tumor necrosis factor (TNF) is an important proinflammatory cytokine that is upregulated in
Alzheimer disease (AD) patients and involved with AD genes. Several TNF promoter …

Inflammatory bowel diseases (IBD)–Crohn's disease (CD) and ulcerative colitis (UC)–are
chronic conditions characterised by relapsing inflammation of the gastrointestinal tract. They …

Tumor necrosis factor-alpha (TNF-α) is a potent immunomediator and proinflammatory
cytokine that has been implicated in the pathogenesis of a large number of human diseases …

TNF‐α is a proinflammatory cytokine that has been implicated in the severity of different
immune‐regulated diseases including autoimmune diseases and transplantation. The gene …

Standard of care for ulcerative colitis involves long‐term pharmacotherapy or colectomy.
Approximately 20% to 30% of patients eventually require a colectomy because patients …

The genes for tumour necrosis factor alpha (TNFα) and lymphotoxin alpha (LTα; TNFβ) are
tandemly arranged in the central region of the MHC. They may, therefore, be of importance …

The pathogenesis of inflammatory bowel disease (IBD) remains unknown, although in
recent years more data have become available. The contribution of genetic and …