Understanding mechanisms of antioxidant action in health and disease

B Halliwell - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Several different reactive oxygen species (ROS) are generated in vivo. They have roles in
the development of certain human diseases whilst also performing physiological functions …

CTLs heterogeneity and plasticity: implications for cancer immunotherapy

S Peng, A Lin, A Jiang, C Zhang, J Zhang, Q Cheng… - Molecular Cancer, 2024 - Springer
Cytotoxic T lymphocytes (CTLs) play critical antitumor roles, encompassing diverse subsets
including CD4+, NK, and γδ T cells beyond conventional CD8+ CTLs. However, definitive …

Laser‐Activatable In Situ Vaccine Enhances Cancer‐Immunity Cycle

Z Wang, T You, Q Su, W Deng, JB Li, S Hu… - Advanced …, 2023 - Wiley Online Library
The immune response in cancer reflects a series of carefully regulated events; however,
current tumor immunotherapies typically address a single key aspect to enhance anti‐tumor …

Role of immune cells and receptors in cancer treatment: an immunotherapeutic approach

AG Mukherjee, UR Wanjari, A Namachivayam… - Vaccines, 2022 - mdpi.com
Cancer immunotherapy moderates the immune system's ability to fight cancer. Due to its
extreme complexity, scientists are working to put together all the puzzle pieces to get a …

Noncoding RNAs as an emerging resistance mechanism to immunotherapies in cancer: basic evidence and therapeutic implications

M Wang, F Yu, P Li - Frontiers in Immunology, 2023 - frontiersin.org
The increasing knowledge in the field of oncoimmunology has led to extensive research into
tumor immune landscape and a plethora of clinical immunotherapy trials in cancer patients …

Resisting T cell attack: tumor-cell-intrinsic defense and reparation mechanisms

B McKenzie, S Valitutti - Trends in Cancer, 2023 - cell.com
Cytotoxic T lymphocytes (CTLs) are antigen-specific killer cells equipped to identify and
eliminate host cells that have been altered through infection or transformation. Both chimeric …

Engineered Outer Membrane Vesicles as Nanosized Immune Cell Engagers for Enhanced Solid Tumor Immunotherapy

J Sun, L Tan, BC Ye, X Bi - ACS nano, 2024 - ACS Publications
Although tumor immunotherapy has achieved significant success in recent years, tackling
solid tumors remains a formidable challenge. Here, we present an approach that utilizes …

[HTML][HTML] Ferroptosis, a subtle talk between immune system and cancer cells: To be or not to be?

Q Zhou, C Tao, J Yuan, F Pan, R Wang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Ferroptosis, an established form of programmed cell death discovered in 2012, is
characterized by an imbalance in iron metabolism, lipid metabolism, and antioxidant …

Thymus-derived hormonal and cellular control of cancer

W Savino, A Lepletier - Frontiers in Endocrinology, 2023 - frontiersin.org
The thymus gland is a central lymphoid organ in which develo** T cell precursors, known
as thymocytes, undergo differentiation into distinct type of mature T cells, ultimately migrating …

Pulsed Photothermal Therapy of Solid Tumors as a Precondition for Immunotherapy

N Farivar, N Khazamipour, ME Roberts, I Nelepcu… - Small, 2024 - Wiley Online Library
Photothermal therapy (PTT) refers to the use of plasmonic nanoparticles to convert
electromagnetic radiation in the near infrared region to heat and kill tumor cells. Continuous …