Advances in flavonoid research: sources, biological activities, and developmental prospectives

B Hao, Z Yang, H Liu, Y Liu, S Wang - Current Issues in Molecular …, 2024 - mdpi.com
At present, the occurrence of a large number of infectious and non-communicable diseases
poses a serious threat to human health as well as to drug development for the treatment of …

[HTML][HTML] Flavonoids as modulators of miRNA expression in pancreatic cancer: Pathways, Mechanisms, And Therapeutic Potential

H Helen, MC Gunawan, P Halim, MR Dinata… - Biomedicine & …, 2024 - Elsevier
Pancreatic cancer (PC) is a complex malignancy, distinguished by its aggressive
characteristics and unfavorable prognosis. Recent developments in understanding the …

Improvement of Chalcone Synthase Activity and High-Efficiency Fermentative Production of (2S)-Naringenin via In Vivo Biosensor-Guided Directed Evolution

Y Tong, N Li, S Zhou, L Zhang, S Xu… - ACS Synthetic …, 2024 - ACS Publications
Chalcone synthase (CHS) catalyzes the rate-limiting step of (2 S)-naringenin (the essential
flavonoid skeleton) biosynthesis. Improving the activity of the CHS by protein engineering …

[HTML][HTML] Nanotechnology and flavonoids: Current research and future perspectives on cardiovascular health

RA Syahputra, A Dalimunthe, ZD Utari, P Halim… - Journal of Functional …, 2024 - Elsevier
The integration of nanotechnology and flavonoid research represents a novel approach to
deliver and stabilize flavonoid, potent natural antioxidants present in various fruits and …

[HTML][HTML] Flavonoids and Flavonoid-Based Nanopharmaceuticals as Promising Therapeutic Strategies for Colorectal Cancer—An Updated Literature Review

A Smeu, I Marcovici, CA Dehelean, SI Dumitrel… - Pharmaceuticals, 2025 - mdpi.com
Colorectal cancer (CRC) represents one of the most serious health issues and the third most
commonly diagnosed cancer worldwide. However, the treatment options for CRC are …

Synaptic plasticity and neuroprotection: The molecular impact of flavonoids on neurodegenerative disease progression

SR Kopalli, T Behl, A Kyada, MM Rekha, M Kundlas… - Neuroscience, 2025 - Elsevier
Flavonoids are a broad family of polyphenolic chemicals that are present in a wide variety of
fruits, vegetables, and medicinal plants. Because of their neuroprotective qualities …

[HTML][HTML] Hydrogel Containing Propolis: Physical Characterization and Evaluation of Biological Activities for Potential Use in the Treatment of Skin Lesions

LMMC Ferreira, NF Cruz, DG Lynch, PF Costa… - Pharmaceuticals, 2024 - mdpi.com
Background: Skin injury affects the integrity of the skin structure and induces the wound
healing process, which is defined by a well-coordinated series of cellular and molecular …

Effect of gelling agents on properties of coumestrol-loaded nanoemulsions–Formulation, skin retention/permeation, antioxidant and skin photoprotective activities

LK Oliveira, DF Argenta, LA Balestrin… - Journal of Drug Delivery …, 2024 - Elsevier
Coumestrol is an isoflavonoid that exhibits antioxidant activity. In this study, hydrogels
containing coumestrol-loaded nanoemulsions were designed to protect the skin against …

[PDF][PDF] Nanoparticle-Encapsulated Plant Polyphenols and Flavonoids as an Enhanced Delivery System for Anti-Acne Therapy

R Puspadewi, T Milanda, M Muhaimin… - …, 2025 - researchgate.net
This study conducted a literature review by searching for articles related to the treatment of
skin infections/wrinkles using nano-delivery systems containing natural compounds. The …

[HTML][HTML] Exploring nanoformulation drug delivery of herbal actives for enhanced therapeutic efficacy: A comprehensive Review

D Sharma, A Gupta, R Rawat, S Sharma, JS Yadav… - Intelligent …, 2024 - Elsevier
Background In this present review we have focused on nanoformulation drug delivery
approach to deliver active drug constituents. As it can minimizes the limitations associated …