The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities …

The orbitofrontal cortex and amygdala are involved in emotion and in motivation, but the
relationship between these functions performed by these brain structures is not clear. To …

The orbitofrontal cortex in primates including humans is the key brain area in emotion, and
in the representation of reward value and in non-reward, that is not obtaining an expected …

Patients with major depressive disorder (MDD) exhibit concurrent deficits in both sensory
and higher-order cognitive processing. Connectome studies have suggested a principal …

The human orbitofrontal cortex, ventromedial prefrontal cortex (vmPFC), and anterior
cingulate cortex are involved in reward processing and thereby in emotion but are also …

Hippocampal and parahippocampal gyrus spatial view neurons in primates respond to the
spatial location being looked at. The representation is allocentric, in that the responses are …

The orbitofrontal cortex represents the reward or affective value of primary reinforcers
including taste, touch, texture, and face expression. It learns to associate other stimuli with …

To advance understanding of brain networks involved in language, the effective connectivity
between 26 cortical regions implicated in language by a community analysis and 360 …

Understanding the neural substrates of depression is crucial for diagnosis and treatment.
Here, we review recent studies of functional and effective connectivity in depression, in …

Pleasure and motivation are important factors for goal-directed behavior and well-being in
both animals and humans. Intact hedonic capacity requires an undisturbed interplay …