Native mass spectrometry (MS) involves the analysis and characterization of
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …

On the basis of many literature measurements, a critical overview is given on essential
noncovalent interactions in synthetic supramolecular complexes, accompanied by analyses …

Crown ethers are heterocycles that, in their simplest form, are cyclic oligomers of dioxane.
The essential repeating unit of any simple crown ether is ethyleneoxy, ie,-CH2CH2O-, which …

This is a review of work pertaining to noncovalent binding interactions involving primarily the
cationic guanidinium group and the anionic sulf [on] ate and phosph [on] ate groups. 1 To a …

For a number of years, soft ionization mass spectrometry has been used for studying
noncovalently bound complexes. An intriguing question in this context is whether MS …

The association-dissociation of noncovalent interactions between protein and ligands, such
as other proteins, carbohydrates, lipids, DNA, or small molecules, are critical events in many …

In the 20 years, since the introduction of electrospray mass spectrometry (ESI‐MS), the use
of this technique in various fields of inorganic, organometallic, and analytical chemistry has …

For many years, analytical mass spectrometry has had numerous supporting roles in the
drug development process, including the assessment of compound purity; quantitation of …

The initial stages of drug discovery are increasingly reliant on development and
improvement of analytical methods to investigate protein–protein and protein–ligand …

The equilibrium dissociation constant (K d) is a major characteristic of affinity complexes and
one of the most frequently determined physicochemical parameters. Despite its significance …