Electrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomics

E Paleček, J Tkáč, M Bartosik, T Bertók… - Chemical …, 2015 - ACS Publications
The present advances in biology are related to progress in genomics, proteomics, and other
“-omics”, including glycomics, working with a large amount of data regarding human and …

Plant lectins as defense proteins against phytophagous insects

G Vandenborre, G Smagghe, EJM Van Damme - Phytochemistry, 2011 - Elsevier
One of the most important direct defense responses in plants against the attack by
phytophagous insects is the production of insecticidal peptides or proteins. One particular …

Lectin microarrays: concept, principle and applications

J Hirabayashi, M Yamada, A Kuno… - Chemical Society …, 2013 - pubs.rsc.org
The lectin microarray is a novel platform for glycan analysis, having emerged only in recent
years. Unlike other conventional methods, eg, liquid chromatography and mass …

Cyclodextrin-based multivalent glycodisplays: Covalent and supramolecular conjugates to assess carbohydrate–protein interactions

Á Martínez, CO Mellet, JMG Fernández - Chemical Society Reviews, 2013 - pubs.rsc.org
Covalent attachment of biorecognizable sugar ligands in several copies at precise positions
of cyclomaltooligosaccharide (cyclodextrin, CD) macrocycles has proven to be an extremely …

Binding sugars: from natural lectins to synthetic receptors and engineered neolectins

J Arnaud, A Audfray, A Imberty - Chemical Society Reviews, 2013 - pubs.rsc.org
The large diversity and complexity of glycan structures together with their crucial role in
many biological or pathological processes require the development of new high-throughput …

Multivalency in heterogeneous glycoenvironments: hetero-glycoclusters,-glycopolymers and-glycoassemblies

JLJ Blanco, CO Mellet, JMG Fernández - Chemical Society Reviews, 2013 - pubs.rsc.org
Despite efficiently imitating functional ligand presentations in terms of valency and density,
most of the reported multivalent carbohydrate prototypes barely reflect the inherent …

[PDF][PDF] Antimicrobial activity of secondary metabolites and lectins from plants

PMG Paiva, FS Gomes, TH Napoleão… - … and education topics …, 2010 - researchgate.net
This review outlines the antimicrobial activity of secondary metabolites and lectins,
compounds usually associated to defense mechanisms of plants. Secondary metabolites …

Plant Lectins Targeting O-Glycans at the Cell Surface as Tools for Cancer Diagnosis, Prognosis and Therapy

G Poiroux, A Barre, EJM Van Damme… - International journal of …, 2017 - mdpi.com
Aberrant O-glycans expressed at the surface of cancer cells consist of membrane-tethered
glycoproteins (T and Tn antigens) and glycolipids (Lewis a, Lewis x and Forssman …

Role of lectin microarrays in cancer diagnosis

P Syed, K Gidwani, H Kekki, J Leivo, K Pettersson… - …, 2016 - Wiley Online Library
The majority of cell differentiation associated tumor markers reported to date are either
glycoproteins or glycolipids. Despite there being a large number of glycoproteins reported …

Glycomic analysis: an array of technologies

L Krishnamoorthy, LK Mahal - ACS chemical biology, 2009 - ACS Publications
Carbohydrates encode biological information necessary for cellular function. The structural
diversity and complexity of these sugar residues have necessitated the creation of novel …