[HTML][HTML] Systematic large-scale assessment of the genetic architecture of left ventricular noncompaction reveals diverse etiologies

F Mazzarotto, MH Hawley, M Beltrami, L Beekman… - Genetics in …, 2021 - Elsevier
Purpose To characterize the genetic architecture of left ventricular noncompaction (LVNC)
and investigate the extent to which it may represent a distinct pathology or a secondary …

Genomics in Egypt: current status and future aspects

EA El-Attar, RM Helmy Elkaffas, SA Aglan… - Frontiers in …, 2022 - frontiersin.org
Egypt is the third most densely inhabited African country. Due to the economic burden and
healthcare costs of overpopulation, genomic and genetic testing is a huge challenge …

From Drug Discovery to Drug Approval: A Comprehensive Review of the Pharmacogenomics Status Quo with a Special Focus on Egypt

FM Elgarhy, A Borham, N Alziny, KR AbdElaal… - …, 2024 - pmc.ncbi.nlm.nih.gov
Pharmacogenomics (PGx) is the hope for the full optimization of drug therapy while
minimizing the accompanying adverse drug events that cost billions of dollars annually …

Ethnicity, consanguinity, and genetic architecture of hypertrophic cardiomyopathy

M Allouba, R Walsh, A Afify, M Hosny… - European heart …, 2023 - academic.oup.com
Aims Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity that
is partly explained by the diversity of genetic variants contributing to disease. Accurate …

Molecular analysis of dilated and left ventricular noncompaction cardiomyopathies in Egyptian children

DA Mehaney, A Haghighi, AK Embaby… - Cardiology in the …, 2022 - cambridge.org
Background: Paediatric cardiomyopathy is a progressive, often lethal disorder and the most
common cause of heart failure in children. Despite its severe outcomes, the genetic …

Structural and Functional Characterization of the Aorta in Hypertrophic Obstructive Cardiomyopathy

AM Ibrahim, M Roshdy, N Latif, A Elsawy… - Circulation: Heart …, 2023 - ahajournals.org
BACKGROUND: Changes in the phenotype and genotype in hypertrophic cardiomyopathy
(HCM) are thought to involve the myocardium as well as extracardiac tissues. Here, we …

Systematic large-scale assessment of the genetic architecture of left ventricular non-compaction reveals diverse aetiologies

SL cases from Swiss… - gimjournal.org
Systematic large-scale assessment of the genetic architecture of left ventricular non- compaction
reveals diverse aetiologies Page 1 1 Systematic large-scale assessment of the genetic …