Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …

The difference in gut microbiota composition between individuals following vegan or
vegetarian diets and those following omnivorous diets is well documented. A plant-based …

Alzheimer's disease (AD) is characterized by an imbalance between production and
clearance of amyloid-β (Aβ) species. Aβ peptides can transform structurally from monomers …

Microtubule affinity regulating kinase (MARK4) is a potential drug target for different types of
cancer as it controls the early step of cell division. In this study, we have screened a series of …

In plants from temperate climates such as Arabidopsis thaliana low, non-freezing
temperatures lead to increased freezing tolerance in a process termed cold acclimation. This …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the deposition of
extracellular amyloid-beta peptide (Aβ) and intracellular neurofibrillar tangles, associated …

Alzheimer's disease (AD) is one of the most common neurodegenerative disorders, with no
cure and preventive therapy. Misfolding and extracellular aggregation of Amyloid-β (Aβ) …

A new mechanism is revealed by which a polyphenol, rosmarinic acid (RA), suppresses
amyloid β (Aβ) accumulation in mice. Here we examined the brains of mice (Alzheimer's …

Protein misfolding and aggregation into fibrillar deposits is a common feature of a large
group of degenerative diseases affecting the central nervous system or peripheral organs …

Amyloid aggregation is a hallmark of several degenerative diseases affecting the brain or
peripheral tissues, whose intermediates (oligomers, protofibrils) and final mature fibrils …