Renin-angiotensin-aldosterone (RAAS): The ubiquitous system for homeostasis and pathologies

S Patel, A Rauf, H Khan, T Abu-Izneid - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Renin-angiotensin-aldosterone system (RAAS) is a vital system of human body, as it
maintains plasma sodium concentration, arterial blood pressure and extracellular volume …

Is Naegleria fowleri an emerging parasite?

SK Maciver, JE Piñero, J Lorenzo-Morales - Trends in parasitology, 2020 - cell.com
Naegleria fowleri causes an uncommon but deadly disease called primary amoebic
meningoencephalitis (PAM). There has been an increase of reported PAM cases …

Naegleria fowleri: Sources of infection, pathophysiology, diagnosis, and management; a review

M Jahangeer, Z Mahmood, N Munir… - Clinical and …, 2020 - Wiley Online Library
Naegleria fowleri, a thermophilic flagellate amoeba known as a “brain‐eating” amoeba, is
the aetiological agent of a perilous and devastating waterborne disease known as primary …

Biology and pathogenesis of Naegleria fowleri

R Siddiqui, IKM Ali, JR Cope, NA Khan - Acta tropica, 2016 - Elsevier
Naegleria fowleri is a protist pathogen that can cause lethal brain infection. Despite decades
of research, the mortality rate related with primary amoebic meningoencephalitis owing to N …

Epidemiology and Clinical Characteristics of Primary Amebic Meningoencephalitis Caused by Naegleria fowleri: A Global Review

R Gharpure, J Bliton, A Goodman… - Clinical Infectious …, 2021 - academic.oup.com
Background Primary amebic meningoencephalitis (PAM) is a rapidly progressive and often
fatal condition caused by the free-living ameba Naegleria fowleri. To estimate the global …

Trends in Naegleria fowleri global research: A bibliometric analysis study

A Ekici, S Alkan, S Aydemir, E Gurbuz, AH Unlu - Acta tropica, 2022 - Elsevier
Naegleria fowleri is one of the most dangerous protozoan agents. This article describes a
bibliometric review of the literature on N. fowleri research indexed in WoS during a 51-year …

Brain-Eating Amoebae: Silver Nanoparticle Conjugation Enhanced Efficacy of Anti-Amoebic Drugs against Naegleria fowleri

K Rajendran, A Anwar, NA Khan… - ACS chemical …, 2017 - ACS Publications
The overall aim of this study was to determine whether conjugation with silver nanoparticles
enhances effects of available drugs against primary amoebic meningoencephalitis due to …

Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae

CA Rice, BL Colon, E Chen, MV Hull… - PLoS Neglected …, 2020 - journals.plos.org
Diseases caused by pathogenic free-living amoebae include primary amoebic
meningoencephalitis (Naegleria fowleri), granulomatous amoebic encephalitis …

Brain-eating amoebae: predilection sites in the brain and disease outcome

TYY Ong, NA Khan, R Siddiqui - Journal of clinical microbiology, 2017 - Am Soc Microbiol
Acanthamoeba spp. and Balamuthia mandrillaris are causative agents of granulomatous
amoebic encephalitis (GAE), while Naegleria fowleri causes primary amoebic …

The therapeutic strategies against Naegleria fowleri

NK Bellini, TM Santos, MTA da Silva… - Experimental …, 2018 - Elsevier
Naegleria fowleri is a pathogenic amoeboflagellate most prominently known for its role as
the etiological agent of the Primary Amoebic Meningoencephalitis (PAM), a disease that …