Aliphatic polycarbonates from cyclic carbonate monomers and their application as biomaterials

W Yu, E Maynard, V Chiaradia, MC Arno… - Chemical …, 2021 - ACS Publications
Aliphatic polycarbonates have gained increased attention as biomaterials largely owing to
their biocompatibility and tunable degradation. Moreover, the ability to introduce functional …

Peptide-drug conjugates and their targets in advanced cancer therapies

P Hoppenz, S Els-Heindl, AG Beck-Sickinger - Frontiers in chemistry, 2020 - frontiersin.org
Cancer became recently the leading cause of death in industrialized countries. Even though
standard treatments achieve significant effects in growth inhibition and tumor elimination …

Actively targeted nanomedicines for precision cancer therapy: Concept, construction, challenges and clinical translation

W Gu, F Meng, R Haag, Z Zhong - Journal of controlled release, 2021 - Elsevier
The development of targeted nanomedicines for cancer therapy has been an utmost focus of
research across different fields including materials science, nanotechnology, biotechnology …

Recent progress in functionalized and targeted polymersomes and chimeric polymeric nanotheranostic platforms for cancer therapy

M Beygi, F Oroojalian, SS Hosseini… - Progress in Materials …, 2023 - Elsevier
The majority of advances in cancer therapy have been achieved based on developments in
public awareness, as well as novel diagnostic and therapeutic modalities. Treatment …

Chemical approaches to synthetic drug delivery systems for systemic applications

D Braatz, M Cherri, M Tully, M Dimde… - Angewandte Chemie …, 2022 - Wiley Online Library
Poor water solubility and low bioavailability of active pharmaceutical ingredients (APIs) are
major causes of friction in the pharmaceutical industry and represent a formidable hurdle for …

Tailor-made semiconducting polymers for second near-infrared photothermal therapy of orthotopic liver cancer

T Sun, J Han, S Liu, X Wang, ZY Wang, Z **e - ACS nano, 2019 - ACS Publications
Liver tumor is one of the most lethal cancers due to its low ratio of surgical resection, high
recurrence rate, and invasiveness. Photothermal therapy (PTT) possesses many …

[HTML][HTML] Polymeric nanocarriers: A promising tool for early diagnosis and efficient treatment of colorectal cancer

M Haider, KZ Zaki, MR El Hamshary, Z Hussain… - Journal of advanced …, 2022 - Elsevier
Background Colorectal cancer (CRC) is the third most prevalent type of cancer for incidence
and second for mortality worldwide. Late diagnosis and inconvenient and expensive current …

Advances in nanoliposomes for the diagnosis and treatment of liver cancer

Y Li, R Zhang, Z Xu, Z Wang - International journal of …, 2022 - Taylor & Francis
The mortality rate of liver cancer is gradually increasing worldwide due to the increasing risk
factors such as fatty liver, diabetes, and alcoholic cirrhosis. The diagnostic methods of liver …

Emerging era of “somes”: Polymersomes as versatile drug delivery carrier for cancer diagnostics and therapy

AK Sharma, P Prasher, AA Aljabali, V Mishra… - Drug delivery and …, 2020 - Springer
Over the past two decades, polymersomes have been widely investigated for the delivery of
diagnostic and therapeutic agents in cancer therapy. Polymersomes are stable polymeric …

Transferrin-binding peptide functionalized polymersomes mediate targeted doxorubicin delivery to colorectal cancer in vivo

Y Wei, X Gu, Y Sun, F Meng, G Storm… - Journal of controlled …, 2020 - Elsevier
Transferrin receptor (TfR) is a promising target validated in the clinical trials for managing
various malignancies. Transferrin (Tf) and single chain antibody fragment can target TfR and …