New technologies for analysis of extracellular vesicles
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
Technical challenges of working with extracellular vesicles
Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with
potential applications in diagnosis, prognosis and therapeutic guidance in most pathological …
potential applications in diagnosis, prognosis and therapeutic guidance in most pathological …
LncRNA RPPH1 promotes colorectal cancer metastasis by interacting with TUBB3 and by promoting exosomes-mediated macrophage M2 polarization
Metastasis is a well-known poor prognostic factor in cancer. However, the mechanisms how
long non-coding RNAs (lncRNAs) regulate metastasis in colorectal cancer (CRC) remain …
long non-coding RNAs (lncRNAs) regulate metastasis in colorectal cancer (CRC) remain …
Coding and noncoding landscape of extracellular RNA released by human glioma stem cells
Tumor-released RNA may mediate intercellular communication and serve as biomarkers.
Here we develop a protocol enabling quantitative, minimally biased analysis of extracellular …
Here we develop a protocol enabling quantitative, minimally biased analysis of extracellular …
[HTML][HTML] Translating RNA sequencing into clinical diagnostics: opportunities and challenges
SA Byron, KR Van Keuren-Jensen… - Nature Reviews …, 2016 - nature.com
With the emergence of RNA sequencing (RNA-seq) technologies, RNA-based biomolecules
hold expanded promise for their diagnostic, prognostic and therapeutic applicability in …
hold expanded promise for their diagnostic, prognostic and therapeutic applicability in …
A comparative study of serum exosome isolation using differential ultracentrifugation and three commercial reagents
Exosomes play a role in cell-to-cell signaling and serve as possible biomarkers. Isolating
exosomes with reliable quality and substantial concentration is a major challenge. Our …
exosomes with reliable quality and substantial concentration is a major challenge. Our …
MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression
Y Teng, Y Ren, X Hu, J Mu, A Samykutty… - Nature …, 2017 - nature.com
Exosomes are emerging mediators of intercellular communication; whether the release of
exosomes has an effect on the exosome donor cells in addition to the recipient cells has not …
exosomes has an effect on the exosome donor cells in addition to the recipient cells has not …
[HTML][HTML] Exosomal long noncoding RNA CRNDE-h as a novel serum-based biomarker for diagnosis and prognosis of colorectal cancer
T Liu, X Zhang, S Gao, F **g, Y Yang, L Du, G Zheng… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Cancer-secreted long non-coding RNAs (lncRNAs) are emerging mediators of cancer-host
cross talk. The aim of our study was to illustrate the clinical significance of the lncRNA …
cross talk. The aim of our study was to illustrate the clinical significance of the lncRNA …
Altered extracellular vesicle concentration, cargo, and function in diabetes
Type 2 diabetes is a chronic age-associated degenerative metabolic disease that reflects
relative insulin deficiency and resistance. Extracellular vesicles (EVs)(exosomes …
relative insulin deficiency and resistance. Extracellular vesicles (EVs)(exosomes …
The extracellular RNA communication consortium: establishing foundational knowledge and technologies for extracellular RNA research
The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …