Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll‐like receptors dictates pathophysiology of COVID‐19 disease

MK Vakil, Y Mansoori, GRL Al‐Awsi… - Journal of Medical …, 2022 - Wiley Online Library
Innate and acquired immunity responses are crucial for viral infection elimination. However,
genetic variations in coding genes may exacerbate the inflammation or initiate devastating …

SARS-CoV-2 evolution and immune escape in immunocompromised patients

EM Scherer, A Babiker, MW Adelman… - … England Journal of …, 2022 - Mass Medical Soc
SARS-CoV-2 Evolution and Immune Escape in Immunocompromised Patients | New England
Journal of Medicine Skip to main content The New England Journal of Medicine homepage …

Targeting B cells and microglia in multiple sclerosis with Bruton tyrosine kinase inhibitors: a review

S Dybowski, S Torke, MS Weber - JAMA neurology, 2023 - jamanetwork.com
Importance Currently, disease-modifying therapies for multiple sclerosis (MS) use 4
mechanisms of action: immune modulation, suppressing immune cell proliferation, inhibiting …

Humoral and cellular responses after COVID-19 vaccination in anti-CD20-treated lymphoma patients

N Liebers, C Speer, L Benning… - Blood, The Journal …, 2022 - ashpublications.org
Three reports address the protection of the vulnerable population of patients with
hematologic malignancies in the face of the ongoing COVID pandemic. The reports suggest …

Longitudinal SARS-CoV-2 mRNA vaccine-induced humoral immune responses in patients with cancer

JC Figueiredo, NM Merin, O Hamid, SY Choi… - Cancer …, 2021 - aacrjournals.org
Longitudinal studies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccine-induced immune responses in patients with cancer are needed to optimize clinical …

SARS-CoV-2 evolution during prolonged infection in immunocompromised patients

AD Marques, J Graham-Wooten, AS Fitzgerald… - MBio, 2024 - journals.asm.org
Prolonged infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in
immunocompromised patients provides an opportunity for viral evolution, potentially leading …

[HTML][HTML] Humoral immune response following SARS-CoV-2 mRNA vaccination concomitant to anti-CD20 therapy in multiple sclerosis

F Novak, AC Nilsson, C Nielsen, DK Holm… - Multiple sclerosis and …, 2021 - Elsevier
Background The immunogenicity of COVID-19 vaccine among patients receiving anti-CD20
monoclonal antibody (Ab) treatment has not been fully investigated. Detectable levels of …

Humoral responses against SARS-CoV-2 and variants of concern after mRNA vaccines in patients with non-Hodgkin lymphoma and chronic lymphocytic leukemia

A Chang, A Akhtar, SL Linderman, L Lai… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Patients with non-Hodgkin lymphoma including chronic lymphocytic leukemia
(NHL/CLL) are at higher risk of severe SARS-CoV-2 infection. We investigated vaccine …

Early administration of remdesivir plus convalescent plasma therapy is effective to treat COVID-19 pneumonia in B-cell depleted patients with hematological …

F Magyari, LI Pinczés, E Páyer, K Farkas, S Ujfalusi… - Annals of …, 2022 - Springer
Patients with hematological malignancies (HMs) are at a higher risk of develo** severe
form and protracted course of COVID-19 disease. We investigated whether the combination …

Combination therapy with casirivimab/imdevimab and remdesivir for protracted SARS-CoV-2 infection in B-cell-depleted patients

MV Dioverti, DC Gaston, CP Morris… - Open forum …, 2022 - academic.oup.com
Profoundly B-cell-depleted patients can have prolonged severe acute respiratory syndrome
coronavirus 2 infections with evidence of active viral replication, due to inability to mount an …