Physical stability of dry powder inhaler formulations
ABSTRACT Introduction: Dry powder inhalers (DPIs) are popular for pulmonary drug
delivery. Various techniques have been employed to produce inhalation drug particles and …
delivery. Various techniques have been employed to produce inhalation drug particles and …
Inhaled formulations and pulmonary drug delivery systems for respiratory infections
Respiratory infections represent a major global health problem. They are often treated by
parenteral administrations of antimicrobials. Unfortunately, systemic therapies of high-dose …
parenteral administrations of antimicrobials. Unfortunately, systemic therapies of high-dose …
Dry powders for oral inhalation free of lactose carrier particles
Dry powder inhaler (DPI) products have traditionally comprised a simple formulation of
micronised drug mixed with a carrier excipient, typically lactose monohydrate. The presence …
micronised drug mixed with a carrier excipient, typically lactose monohydrate. The presence …
[HTML][HTML] Influence of physical properties of carrier on the performance of dry powder inhalers
T Peng, S Lin, B Niu, X Wang, Y Huang, X Zhang… - … pharmaceutica sinica B, 2016 - Elsevier
Dry powder inhalers (DPIs) offer distinct advantages as a means of pulmonary drug delivery
and have attracted much attention in the field of pharmaceutical science. DPIs commonly …
and have attracted much attention in the field of pharmaceutical science. DPIs commonly …
Pulmonary drug delivery by powder aerosols
MY Yang, JGY Chan, HK Chan - Journal of Controlled Release, 2014 - Elsevier
The efficacy of pharmaceutical aerosols relates to its deposition in the clinically relevant
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …
Emerging inhalation aerosol devices and strategies: where are we headed?
Novel inhaled therapeutics including antibiotics, vaccines and anti-hypertensives, have led
to innovations in designing suitable delivery systems. These emerging design technologies …
to innovations in designing suitable delivery systems. These emerging design technologies …
Develo** an efficient and reliable dry powder inhaler for pulmonary drug delivery–a review for multidisciplinary researchers
Pulmonary drug delivery is the focus of much research and development because of its
great potential to produce maximum therapeutic benefit. Among the available options the dry …
great potential to produce maximum therapeutic benefit. Among the available options the dry …
Influence of particle properties on powder bulk behaviour and processability
Understanding interparticle interactions in powder systems is crucial to pharmaceutical
powder processing. Nevertheless, there remains a great challenge in identifying the key …
powder processing. Nevertheless, there remains a great challenge in identifying the key …
Delivery technologies for orally inhaled products: an update
Orally inhaled products have well-known benefits. They allow for effective local
administration of many drugs for the treatment of pulmonary disease, and they allow for …
administration of many drugs for the treatment of pulmonary disease, and they allow for …
Powder production and particle engineering for dry powder inhaler formulations
Dry powder inhalers have become increasingly attractive for pulmonary delivery of locally
and systemically effective medications. In comparison to the liquid counterparts, such as …
and systemically effective medications. In comparison to the liquid counterparts, such as …