Physical stability of dry powder inhaler formulations

N Shetty, D Cipolla, H Park, QT Zhou - Expert opinion on drug …, 2020 - Taylor & Francis
ABSTRACT Introduction: Dry powder inhalers (DPIs) are popular for pulmonary drug
delivery. Various techniques have been employed to produce inhalation drug particles and …

Inhaled formulations and pulmonary drug delivery systems for respiratory infections

QT Zhou, SSY Leung, P Tang, T Parumasivam… - Advanced drug delivery …, 2015 - Elsevier
Respiratory infections represent a major global health problem. They are often treated by
parenteral administrations of antimicrobials. Unfortunately, systemic therapies of high-dose …

Dry powders for oral inhalation free of lactose carrier particles

AM Healy, MI Amaro, KJ Paluch, L Tajber - Advanced drug delivery reviews, 2014 - Elsevier
Dry powder inhaler (DPI) products have traditionally comprised a simple formulation of
micronised drug mixed with a carrier excipient, typically lactose monohydrate. The presence …

[HTML][HTML] Influence of physical properties of carrier on the performance of dry powder inhalers

T Peng, S Lin, B Niu, X Wang, Y Huang, X Zhang… - … pharmaceutica sinica B, 2016 - Elsevier
Dry powder inhalers (DPIs) offer distinct advantages as a means of pulmonary drug delivery
and have attracted much attention in the field of pharmaceutical science. DPIs commonly …

Pulmonary drug delivery by powder aerosols

MY Yang, JGY Chan, HK Chan - Journal of Controlled Release, 2014 - Elsevier
The efficacy of pharmaceutical aerosols relates to its deposition in the clinically relevant
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …

Emerging inhalation aerosol devices and strategies: where are we headed?

QT Zhou, P Tang, SSY Leung, JGY Chan… - Advanced drug delivery …, 2014 - Elsevier
Novel inhaled therapeutics including antibiotics, vaccines and anti-hypertensives, have led
to innovations in designing suitable delivery systems. These emerging design technologies …

Develo** an efficient and reliable dry powder inhaler for pulmonary drug delivery–a review for multidisciplinary researchers

N Islam, MJ Cleary - Medical engineering & physics, 2012 - Elsevier
Pulmonary drug delivery is the focus of much research and development because of its
great potential to produce maximum therapeutic benefit. Among the available options the dry …

Influence of particle properties on powder bulk behaviour and processability

UV Shah, V Karde, C Ghoroi, JYY Heng - International journal of …, 2017 - Elsevier
Understanding interparticle interactions in powder systems is crucial to pharmaceutical
powder processing. Nevertheless, there remains a great challenge in identifying the key …

Delivery technologies for orally inhaled products: an update

C Moon, HDC Smyth, AB Watts, RO Williams III - AAPS PharmSciTech, 2019 - Springer
Orally inhaled products have well-known benefits. They allow for effective local
administration of many drugs for the treatment of pulmonary disease, and they allow for …

Powder production and particle engineering for dry powder inhaler formulations

YW Lin, J Wong, L Qu, HK Chan… - Current pharmaceutical …, 2015 - benthamdirect.com
Dry powder inhalers have become increasingly attractive for pulmonary delivery of locally
and systemically effective medications. In comparison to the liquid counterparts, such as …