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Non-coding RNAs: the riddle of the transcriptome and their perspectives in cancer
Non-coding RNAs (ncRNAs) constitute a heterogeneous group of RNA molecules in terms
of biogenesis, biological function as well as length and structure. These biological …
of biogenesis, biological function as well as length and structure. These biological …
Identification of Two Novel Circular RNAs Deriving from BCL2L12 and Investigation of Their Potential Value as a Molecular Signature in Colorectal Cancer
The utility of circular RNAs (circRNAs) as molecular biomarkers has recently emerged.
However, only a handful of them have already been studied in colorectal cancer (CRC). The …
However, only a handful of them have already been studied in colorectal cancer (CRC). The …
Kallikrein-related peptidases and associated microRNAs as promising prognostic biomarkers in gastrointestinal malignancies
Gastrointestinal (GI) malignancies represent a wide spectrum of diseases of the GI tract and
its accessory digestive organs, including esophageal (EC), gastric (GC), hepatocellular …
its accessory digestive organs, including esophageal (EC), gastric (GC), hepatocellular …
Identification of a novel human E‐cadherin splice variant and assessment of its effects upon EMT‐related events
ML Matos, L Lapyckyj, M Rosso… - Journal of cellular …, 2017 - Wiley Online Library
Epithelial Cadherin (E‐cadherin) is involved in calcium‐dependent cell–cell adhesion and
signal transduction. The E‐cadherin decrease/loss is a hallmark of Epithelial to …
signal transduction. The E‐cadherin decrease/loss is a hallmark of Epithelial to …
Novel alternative splice variants of the human protein arginine methyltransferase 1 (PRMT1) gene, discovered using next-generation sequencing
Next-generation sequencing (NGS) technology is highly expected to help researchers
disclose the complexity of alternative splicing and understand its association with …
disclose the complexity of alternative splicing and understand its association with …
[HTML][HTML] Unraveling novel survivin mRNA transcripts in cancer cells using an in-house developed targeted high-throughput sequencing approach
The human baculoviral IAP repeat containing 5 (BIRC5), also known as survivin, is a
conserved member of the inhibitor of apoptosis protein (IAPs) family, which is normally …
conserved member of the inhibitor of apoptosis protein (IAPs) family, which is normally …
Positive BCL2L12 expression predicts favorable prognosis in patients with laryngeal squamous cell carcinoma
AI Giotakis, AC Lazaris, A Kataki… - Cancer …, 2019 - journals.sagepub.com
BACKGROUND: Laryngeal squamous cell carcinoma (LSCC) constitutes the third most
frequent head and neck cancer. Several tissue biomarkers have been studied for their …
frequent head and neck cancer. Several tissue biomarkers have been studied for their …
Quantitative analysis and study of the mRNA expression levels of apoptotic genes BCL2, BAX and BCL2L12 in the articular cartilage of an animal model of …
A Kourtis, PG Adamopoulos, A Papalois… - Annals of …, 2018 - pmc.ncbi.nlm.nih.gov
Background Given that apoptosis of chondrocytes is one of the most important factors
related to the pathogenesis of osteoarthritis (OA), the recent research interest adds progress …
related to the pathogenesis of osteoarthritis (OA), the recent research interest adds progress …
Molecular cloning of novel transcripts of human kallikrein-related peptidases 5, 6, 7, 8 and 9 (KLK5 – KLK9), using Next-generation sequencing
Alternative splicing of cancer-related genes is a common cellular mechanism accounting for
cancer cell transcriptome complexity and affecting cell cycle control, proliferation, apoptosis …
cancer cell transcriptome complexity and affecting cell cycle control, proliferation, apoptosis …
Alternative Splicing Detection Tool—a novel PERL algorithm for sensitive detection of splicing events, based on next-generation sequencing data analysis
PG Adamopoulos… - Annals of …, 2018 - pmc.ncbi.nlm.nih.gov
Next-generation sequencing (NGS) can provide researchers with high impact information
regarding alternative splice variants or transcript identifications. However, the enormous …
regarding alternative splice variants or transcript identifications. However, the enormous …