[HTML][HTML] GEIS guidelines for gastrointestinal sarcomas (GIST)

A Poveda, XG Del Muro, JA López-Guerrero… - Cancer treatment …, 2017 - Elsevier
Gastrointestinal stromal sarcomas (GISTs) are the most common mesenchymal tumours
originating in the digestive tract. They have a characteristic morphology, are generally …

Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma

MM Gounder, NP Agaram, SE Trabucco… - Nature …, 2022 - nature.com
There are more than 70 distinct sarcomas, and this diversity complicates the development of
precision-based therapeutics for these cancers. Prospective comprehensive genomic …

Management of primary retroperitoneal sarcoma (RPS) in the adult: a consensus approach from the Trans-Atlantic RPS Working Group

Trans-Atlantic RPS Working Group - Annals of surgical oncology, 2015 - Springer
Background Retroperitoneal soft tissue sarcomas (RPS) are rare tumors that include several
well-defined histologic subtypes. Although surgery is the mainstay of curative therapy, no …

A Phase I, dose-finding study in patients with advanced solid malignancies of the oral γ-secretase inhibitor PF-03084014

WA Messersmith, GI Shapiro, JM Cleary, A Jimeno… - Clinical Cancer …, 2015 - AACR
Purpose: To estimate the maximum tolerated dose (MTD) for continuous oral administration
of the γ-secretase inhibitor PF-03084014, determine the recommended phase II dose …

Gastrointestinal stromal tumors: who should get imatinib and for how long?

VP Balachandran, RP DeMatteo - Advances in surgery, 2014 - advancessurgery.com
Imatinib is the first-line therapy for patients with unresectable, recurrent, or metastatic
gastrointestinal stromal tumor (GIST), except those with PDGFRA D842V mutations, which …

Spontaneous regression of primary abdominal wall desmoid tumors: more common than previously thought

S Bonvalot, N Ternès, M Fiore, G Bitsakou… - Annals of Surgical …, 2013 - Springer
Purpose The relevance of the initial observational approach for desmoid tumors (DTs)
remains unclear. We investigated a new conservative management treatment for primary …

CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study

C Colombo, R Miceli, AJ Lazar, F Perrone, RE Pollock… - Cancer, 2013 - Wiley Online Library
BACKGROUND A role for the serine to phenylalanine substitution at codon 45 (the S45F
mutation) in the catenin (cadherin‐associated protein) β‐1 (CTNNB1) gene as a molecular …

Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion

S Atay, S Banskota, J Crow, G Sethi… - Proceedings of the …, 2014 - National Acad Sciences
During tumor development, constant interplay occurs between tumor cells and surrounding
stromal cells. We report evidence that gastrointestinal stromal tumor (GIST) cells invade the …

Carbon fiber intramedullary nails reduce artifact in postoperative advanced imaging

MN Zimel, S Hwang, ER Riedel, JH Healey - Skeletal radiology, 2015 - Springer
Objective This study assessed whether radiolucent carbon fiber reinforced-
polyetheretherketone (CFR-PEEK) intramedullary nails decreased hardware artifact on …

Diagnostic accuracy of percutaneous biopsy in retroperitoneal sarcoma

LM Almond, F Tirotta, H Tattersall… - Journal of British …, 2019 - academic.oup.com
Background Percutaneous biopsy is recommended before surgery for suspected
retroperitoneal sarcoma (RPS) to confirm the histological diagnosis and guide surgical …