Key concepts of clinical trials: a narrative review
The recent focus of federal funding on comparative effectiveness research underscores the
importance of clinical trials in the practice of evidence-based medicine and health care …
importance of clinical trials in the practice of evidence-based medicine and health care …
Issues in outcomes research: an overview of randomization techniques for clinical trials
Objective: To review and describe randomization techniques used in clinical trials, including
simple, block, stratified, and covariate adaptive techniques. Background: Clinical trials are …
simple, block, stratified, and covariate adaptive techniques. Background: Clinical trials are …
Ensayos clínicos aleatorizados: variantes, métodos de aleatorización, análisis, consideraciones éticas y regulación
E Lazcano-Ponce, E Salazar-Martínez… - Salud pública de …, 2004 - medigraphic.com
“Me levanté muy temprano para visitarlos, con la esperanza de encontrar a aquellos a
quienes había administrado un medicamento digestivo. Sintiendo un poco de dolor, sus …
quienes había administrado un medicamento digestivo. Sintiendo un poco de dolor, sus …
Efficacy of dialectical behavior therapy for adolescents at high risk for suicide: a randomized clinical trial
E McCauley, MS Berk, JR Asarnow, M Adrian… - JAMA …, 2018 - jamanetwork.com
Importance Suicide is a leading cause of death among 10-to 24-year-old individuals in the
United States; evidence on effective treatment for adolescents who engage in suicidal and …
United States; evidence on effective treatment for adolescents who engage in suicidal and …
Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial
Background Primary angle-closure glaucoma is a leading cause of irreversible blindness
worldwide. In early-stage disease, intraocular pressure is raised without visual loss …
worldwide. In early-stage disease, intraocular pressure is raised without visual loss …
Effect of low-intensity physical activity and moderate-to high-intensity physical exercise during adjuvant chemotherapy on physical fitness, fatigue, and chemotherapy …
Purpose We evaluated the effectiveness of a low-intensity, home-based physical activity
program (Onco-Move) and a moderate-to high-intensity, combined supervised resistance …
program (Onco-Move) and a moderate-to high-intensity, combined supervised resistance …
Music improves social communication and auditory–motor connectivity in children with autism
Music has been identified as a strength in people with Autism Spectrum Disorder; however,
there is currently no neuroscientific evidence supporting its benefits. Given its universal …
there is currently no neuroscientific evidence supporting its benefits. Given its universal …
Pretreatment with anti-thymocyte globulin versus no anti-thymocyte globulin in patients with haematological malignancies undergoing haemopoietic cell …
Background Pretreatment with anti-thymocyte globulin (ATG) decreases the occurrence of
chronic graft-versus-host disease (CGVHD) after haemopoietic cell transplantation from an …
chronic graft-versus-host disease (CGVHD) after haemopoietic cell transplantation from an …
The risks and rewards of covariate adjustment in randomized trials: an assessment of 12 outcomes from 8 studies
Background Adjustment for prognostic covariates can lead to increased power in the
analysis of randomized trials. However, adjusted analyses are not often performed in …
analysis of randomized trials. However, adjusted analyses are not often performed in …
In pursuit of balance: Randomization in practice in development field experiments
We present new evidence on the randomization methods used in existing experiments, and
new simulations comparing these methods. We find that many papers do not describe the …
new simulations comparing these methods. We find that many papers do not describe the …