Since first described in the early 1900s, Alzheimer's disease (AD) has risen exponentially in
prevalence and concern. Research still drives to understand the etiology and pathogenesis …

Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …

Cognitive dysfunction (CD) in heart failure (HF) adversely affects treatment compliance and
quality of life. Although ryanodine receptor type 2 (RyR2) has been linked to cardiac muscle …

Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …

Heart failure (HF) is a complex clinical syndrome with multiple interactions between the
failing myocardium and cerebral (dys‐) functions. Bi‐directional feedback interactions …

White matter hyperintensities are frequent on neuroimaging of older people and are a key
feature of cerebral small vessel disease. They are commonly attributed to chronic …

Cerebral small vessel disease (CSVD) has emerged as a common factor driving age-
dependent diseases, including stroke and dementia. CSVD-related dementia will affect a …

Diseases affecting the brain contribute to a substantial proportion of morbidity and mortality
in the general population. Conditions such as stroke, dementia and cognitive impairment …

Medial temporal lobe dependent cognitive functions are highly vulnerable to hypoxia in the
hippocampal region, yet little is known about the relationship between the richness of …

It has been estimated that 5.1 million Americans suffer from heart failure. Cognitive
impairment has been described as a consequence of heart failure in numerous studies …