Visible-light induced direct C (sp3)-H functionalization: recent advances and future prospects
The direct activation of inert saturated C–H bonds for selective functionalization has long
been a significant challenge in organic synthesis. The past few decades have witnessed the …
been a significant challenge in organic synthesis. The past few decades have witnessed the …
Sulfonimidamides in medicinal and agricultural chemistry
The synthesis and evaluation of structural analogues and isosteres are of central importance
in medicinal and agricultural chemistry. The sulfonamide functional group represents one of …
in medicinal and agricultural chemistry. The sulfonamide functional group represents one of …
Data-mining for sulfur and fluorine: An evaluation of pharmaceuticals to reveal opportunities for drug design and discovery: Miniperspective
Among carbon, hydrogen, oxygen, and nitrogen, sulfur and fluorine are both leading
constituents of the pharmaceuticals that comprise our medicinal history. In efforts to stimulate …
constituents of the pharmaceuticals that comprise our medicinal history. In efforts to stimulate …
Phosphine/photoredox catalyzed anti-Markovnikov hydroamination of olefins with primary sulfonamides via α-scission from phosphoranyl radicals
New strategies to access radicals from common feedstock chemicals hold the potential to
broadly impact synthetic chemistry. We report a dual phosphine and photoredox catalytic …
broadly impact synthetic chemistry. We report a dual phosphine and photoredox catalytic …
Metal chelates of sulfafurazole azo dye derivative: synthesis, structure affirmation, antimicrobial, antitumor, DNA binding, and molecular docking simulation
HA El-Ghamry, RO Al-Ziyadi… - Bioinorganic …, 2023 - Wiley Online Library
A series of divalent and one trivalent metal chelates of the azo ligand resulting from coupling
of sulfafurazole diazonium chloride with resorcinol have been designed and synthesized …
of sulfafurazole diazonium chloride with resorcinol have been designed and synthesized …
Silyl radical-mediated activation of sulfamoyl chlorides enables direct access to aliphatic sulfonamides from alkenes
Single electron reduction is more challenging for sulfamoyl chlorides than sulfonyl chlorides.
However, sulfamoyl and sulfonyl chlorides can be easily activated by Cl-atom abstraction by …
However, sulfamoyl and sulfonyl chlorides can be easily activated by Cl-atom abstraction by …
Photocatalytic late-stage functionalization of sulfonamides via sulfonyl radical intermediates
A plethora of drug molecules and agrochemicals contain the sulfonamide functional group.
However, sulfonamides are seldom viewed as synthetically useful functional groups. To …
However, sulfonamides are seldom viewed as synthetically useful functional groups. To …
Biodegradation of sulfamethoxazole and other sulfonamides by Achromobacter denitrificans PR1
This study aimed to isolate and characterize a microbial culture able to degrade
sulfonamides. Sulfamethoxazole (SMX)-degrading microorganisms were enriched from …
sulfonamides. Sulfamethoxazole (SMX)-degrading microorganisms were enriched from …
Metal‐Free Electrochemical Synthesis of Sulfonamides Directly from (Hetero)arenes, SO2, and Amines
SP Blum, T Karakaya, D Schollmeyer… - Angewandte Chemie …, 2021 - Wiley Online Library
Sulfonamides are among the most important chemical motifs in pharmaceuticals and
agrochemicals. However, there is no methodology to directly introduce the sulfonamide …
agrochemicals. However, there is no methodology to directly introduce the sulfonamide …
Photoredox alkylation of sulfinylamine enables the synthesis of highly functionalized sulfinamides and S (VI) derivatives
L Li, S Zhang, Y Chen, X Cui, G Zhao, Z Tang… - ACS Catalysis, 2022 - ACS Publications
Sulfinamides have widespread applications in organic synthesis, especially for the
preparation of S (VI) derivatives such as sulfonimidamide and sulfonimidate ester. The …
preparation of S (VI) derivatives such as sulfonimidamide and sulfonimidate ester. The …