Malaria is a devastating infectious disease that is caused by blood-borne apicomplexan
parasites of the genus Plasmodium. These pathogens have a complex lifecycle, which …

Plasmodium sporozoites are the product of a complex developmental process in the
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …

The life cycles of many parasites involve transitions between disparate host species,
requiring these parasites to go through multiple developmental stages adapted to each of …

Commitment to and completion of sexual development are essential for malaria parasites
(protists of the genus Plasmodium) to be transmitted through mosquitoes. The molecular …

Clonally variant expression of surface antigens allows the malaria parasite Plasmodium
falciparum to evade immune recognition during blood stage infection and secure malaria …

Underlying the development of malaria parasites within erythrocytes and the resulting
pathogenicity is a hardwired program that secures proper timing of gene transcription and …

The mosquito midgut stages of malaria parasites are crucial for establishing an infection in
the insect vector and to thus ensure further spread of the pathogen. Parasite development in …

The apicomplexan parasite Cryptosporidium is a leading global cause of severe diarrhoeal
disease and an important contributor to early childhood mortality. Currently, there are no …

Background Apicomplexan parasites replicate by varied and unusual processes where the
typically eukaryotic expansion of cellular components and chromosome cycle are …

The unique relapsing nature of Plasmodium vivax infection is a major barrier to malaria
eradication. Upon infection, dormant liver-stage forms, hypnozoites, linger for weeks to …