Ewing sarcoma is the second most frequent bone tumour of childhood and adolescence that
can also arise in soft tissue. Ewing sarcoma is a highly aggressive cancer, with a survival of …

Structural gene rearrangements resulting in gene fusions are frequent events in solid
tumours. The identification of certain activating fusions can aid in the diagnosis and effective …

The diagnosis of pancreatic neuroendocrine tumours (PanNETs) is increasing owing to
more sensitive detection methods, and this increase is creating challenges for clinical …

Alpha-synuclein is a presynaptic protein that forms abnormal cytoplasmic aggregates in
Lewy body disorders. Although nuclear alpha-synuclein localization has been described, its …

Pediatric Ewing sarcoma is characterized by the expression of chimeric fusions of EWS and
ETS family transcription factors, representing a paradigm for studying cancers driven by …

Acclaimed by the worldwide medical community as" a staple reference text in the medical
oncologist's library"(JAMA), DeVita, Hellman, and Rosenberg's Cancer: Principles and …

Here's your ideal reference on the diagnosis of tumors of the skeletal muscles, connective
tissue, fat, and related structures. No other textbook matches its scope and depth of …

The purpose of this expert review is to discuss the impact of nanotechnology in the treatment
of the major health threats including cancer, infections, metabolic diseases, autoimmune …

Fusion oncogenes (FOs) are common in many cancer types and are powerful drivers of
tumor development. Because their expression is exclusive to cancer cells and their …

We have examined the structure and expression of the products associated with the t (2;
13)(q35; q14) translocation associated with alveolar rhabdomyosarcoma. The chromosome …