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Cognitive impairment and dementia after stroke: design and rationale for the DISCOVERY study
Stroke is a leading cause of the adult disability epidemic in the United States, with a major
contribution from poststroke cognitive impairment and dementia (PSCID), the rates of which …
contribution from poststroke cognitive impairment and dementia (PSCID), the rates of which …
Pathogenetic pathways of cognitive dysfunction and dementia in metabolic syndrome
YY Borshchev, YP Uspensky, MM Galagudza - Life sciences, 2019 - Elsevier
The prevalence of dementia worldwide is growing at an alarming rate. A number of studies
and meta-analyses have provided evidence for increased risk of dementia in patients with …
and meta-analyses have provided evidence for increased risk of dementia in patients with …
Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts
Background Post-stroke cognitive impairment (PSCI) occurs in approximately half of people
in the first year after stroke. Infarct location is a potential determinant of PSCI, but a …
in the first year after stroke. Infarct location is a potential determinant of PSCI, but a …
Strategic white matter hyperintensity locations for cognitive impairment: a multicenter lesion‐symptom map** study in 3525 memory clinic patients
Introduction Impact of white matter hyperintensities (WMH) on cognition likely depends on
lesion location, but a comprehensive map of strategic locations is lacking. We aimed to …
lesion location, but a comprehensive map of strategic locations is lacking. We aimed to …
[HTML][HTML] Anatomy of phonemic and semantic fluency: A lesion and disconnectome study in 1231 stroke patients
Disturbances of semantic and phonemic fluency are common after brain damage, as a
manifestation of language, executive, or memory dysfunction. Lesion-symptom map** …
manifestation of language, executive, or memory dysfunction. Lesion-symptom map** …
[HTML][HTML] Post-stroke cognitive impairment: pathophysiological insights into brain disconnectome from advanced neuroimaging analysis techniques
The neurological symptoms of stroke have traditionally provided the foundation for functional
map** of the brain. However, there are many unresolved aspects in our understanding of …
map** of the brain. However, there are many unresolved aspects in our understanding of …
[HTML][HTML] Cerebral amyloid burden is associated with white matter hyperintensity location in specific posterior white matter regions
White matter hyperintensities (WMHs) are a common manifestation of cerebral small vessel
disease. WMHs are also frequently observed in patients with familial and sporadic …
disease. WMHs are also frequently observed in patients with familial and sporadic …
Late-life depression accentuates cognitive weaknesses in older adults with small vessel disease
Neuroimaging features of small vessel disease (SVD) are highly prevalent in older
adulthood and associated with significant variability in clinical symptoms, yet the factors …
adulthood and associated with significant variability in clinical symptoms, yet the factors …
[HTML][HTML] Cerebral white matter hyperintensity volumes: normative age-and sex-specific values from 15 population-based cohorts comprising 14,876 individuals
White matter hyperintensities (WMH) increase with age, with marked interindividual
variation. There is a need for normative data by age and sex, to improve individualized WMH …
variation. There is a need for normative data by age and sex, to improve individualized WMH …
[HTML][HTML] White matter hyperintensity volume and poststroke cognition: an individual patient data pooled analysis of 9 ischemic stroke cohort studies
BACKGROUND: White matter hyperintensities (WMH) are associated with cognitive
dysfunction after ischemic stroke. Yet, uncertainty remains about affected domains, the role …
dysfunction after ischemic stroke. Yet, uncertainty remains about affected domains, the role …