Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

The delivery of therapeutic agents faces significant hurdles posed by the endo-lysosomal
pathway, a bottleneck that hampers clinical effectiveness. This comprehensive review …

Endosomal entrapment has remained the major bottleneck for cytosolic delivery of
nanoparticle‐based delivery systems. Uncovering fundamentally new pathways for …

The balance of pro-apoptotic and pro-survival proteins defines a cell's fate. These processes
are controlled through an interdependent and finely tuned protein network that enables …

The therapeutic outcome of chemodynamic therapy (CDT) is greatly hindered by the
presence of oxidative damage repair proteins (MTH1) inside cancer cells. These oxidative …

Polymeric nanocarriers (PNCs) are versatile drug delivery vehicles capable of delivering a
variety of therapeutics. Quantitatively monitoring their uptake in biological systems is …

Delivery of therapeutics specifically to the disease site is the final goal for the field of drug
discovery. Considerable efforts in understanding disease biology have contributed to …

Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs of interest …