Abstract Bile Salt Hydrolase (BSH) is a bacterial enzyme (EC 3.5. 1.24) that initiates the
crucial deconjugation of bile acids (BAs), a process necessary for their transformation into …

Bile acid (BA) species and the gut microbiota (GM) contribute to intestinal mucosa
homeostasis. BAs shape the GM and, conversely, intestinal bacteria with bile salt hydrolase …

Background Bile salt hydrolase plays an important role in bile acid-mediated signaling
pathways, which regulate lipid absorption, glucose metabolism, and energy homeostasis …

Gut bacteria influence human physiology by chemically modifying host-synthesized primary
bile acids. These modified bile acids, known as secondary bile acids, can act as signaling …

The gut microbiota is increasingly recognised as a key player in influencing human health
and changes in the gut microbiota have been strongly linked with many non-communicable …

Dyslipidemia, specifically abnormal levels of low-density lipoprotein cholesterol (LDL-C), is
an important risk factor of cardiovascular disease. Evidence showing the promising abilities …

Bile salt hydrolase (BSH) and penicillin V acylase (PVA) are related enzymes that are
classified as choloylglycine hydrolases (CGH). BSH enzymes have attracted significant …

Several risk factors are associated with gallstone disease after bariatric surgery, but the
underlying pathophysiological mechanisms of gallstone formation are unclear. We …

Cirrhosis is the end stage of chronic liver diseases like chronic hepatitis B. In China,
hepatitis B accounts for around 60% of cases of cirrhosis. So far, clinical and laboratory …

Background: Cholelithiasis is one of the more common complications following bariatric
surgery. This may be related to the rapid weight loss during this period, although the exact …