ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …
Imaging suicidal thoughts and behaviors: a comprehensive review of 2 decades of neuroimaging studies
Identifying brain alterations that contribute to suicidal thoughts and behaviors (STBs) are
important to develop more targeted and effective strategies to prevent suicide. In the last …
important to develop more targeted and effective strategies to prevent suicide. In the last …
Mendelian randomization analyses support causal relationships between brain imaging-derived phenotypes and risk of psychiatric disorders
Observational studies have reported the correlations between brain imaging-derived
phenotypes (IDPs) and psychiatric disorders; however, whether the relationships are causal …
phenotypes (IDPs) and psychiatric disorders; however, whether the relationships are causal …
Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group
The regional distribution of white matter (WM) abnormalities in schizophrenia remains poorly
understood, and reported disease effects on the brain vary widely between studies. In an …
understood, and reported disease effects on the brain vary widely between studies. In an …
Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia
We report results from the Bipolar Exome (BipEx) collaboration analysis of whole-exome
sequencing of 13,933 patients with bipolar disorder (BD) matched with 14,422 controls. We …
sequencing of 13,933 patients with bipolar disorder (BD) matched with 14,422 controls. We …
Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis
Background Neuroimaging studies have shown structural alterations in several brain
regions in children and adults with attention deficit hyperactivity disorder (ADHD). Through …
regions in children and adults with attention deficit hyperactivity disorder (ADHD). Through …
Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group
Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well
understood. Structural brain differences have been associated with BD, but results from …
understood. Structural brain differences have been associated with BD, but results from …
The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management
Bipolar disorder is heterogeneous in phenomenology, illness trajectory, and response to
treatment. Despite evidence for the efficacy of multimodality interventions, the majority of …
treatment. Despite evidence for the efficacy of multimodality interventions, the majority of …
Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study
Progressive functional decline in the epilepsies is largely unexplained. We formed the
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in …
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in …
Cortical and subcortical brain morphometry differences between patients with autism spectrum disorder and healthy individuals across the lifespan: results from the …
Objective: Neuroimaging studies show structural differences in both cortical and subcortical
brain regions in children and adults with autism spectrum disorder (ASD) compared with …
brain regions in children and adults with autism spectrum disorder (ASD) compared with …