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Site-selective orientated immobilization of antibodies and conjugates for immunodiagnostics development
Immobilized antibody systems are the key to develop efficient diagnostics and separations
tools. In the last decade, developments in the field of biomolecular engineering and …
tools. In the last decade, developments in the field of biomolecular engineering and …
[HTML][HTML] Factors influencing properties of spider silk coatings and their interactions within a biological environment
VT Trossmann, S Lentz, T Scheibel - Journal of Functional Biomaterials, 2023 - mdpi.com
Biomaterials are an indispensable part of biomedical research. However, although many
materials display suitable application-specific properties, they provide only poor …
materials display suitable application-specific properties, they provide only poor …
Genetic Functionalization of Protein-Based Biomaterials via Protein Fusions
GG Mendes, B Faulk, B Kaparthi, AR Irion… - …, 2024 - ACS Publications
Proteins implement many useful functions, including binding ligands with unparalleled
affinity and specificity, catalyzing stereospecific chemical reactions, and directing cell …
affinity and specificity, catalyzing stereospecific chemical reactions, and directing cell …
Self-assembly of recombinant silk as a strategy for chemical-free formation of bioactive coatings: A real-time study
L Nilebäck, J Hedin, M Widhe, LS Floderus… - …, 2017 - ACS Publications
Functionalization of biomaterials with biologically active peptides can improve their
performance after implantation. By genetic fusion to self-assembling proteins, the functional …
performance after implantation. By genetic fusion to self-assembling proteins, the functional …
Recombinant protein polymer-antibody conjugates for applications in nanotechnology and biomedicine
AG Goncalves, EJ Hartzell, MO Sullivan… - Advanced Drug Delivery …, 2022 - Elsevier
Currently, there are over 100 antibody-based therapeutics on the market for the treatment of
various diseases. The increasing importance of antibody treatment is further highlighted by …
various diseases. The increasing importance of antibody treatment is further highlighted by …
Bioselectivity of silk protein-based materials and their bio-inspired applications
H Bargel, VT Trossmann, C Sommer… - Beilstein Journal of …, 2022 - beilstein-journals.org
Adhesion to material surfaces is crucial for almost all organisms regarding subsequent
biological responses. Mammalian cell attachment to a surrounding biological matrix is …
biological responses. Mammalian cell attachment to a surrounding biological matrix is …
Silk–silk interactions between silkworm fibroin and recombinant spider silk fusion proteins enable the construction of bioactive materials
L Nileback, D Chouhan, R Jansson… - … Applied Materials & …, 2017 - ACS Publications
Natural silk is easily accessible from silkworms and can be processed into different formats
suitable as biomaterials and cell culture matrixes. Recombinant DNA technology enables …
suitable as biomaterials and cell culture matrixes. Recombinant DNA technology enables …
Silk materials functionalized via genetic engineering for biomedical applications
T Deptuch, H Dams-Kozlowska - Materials, 2017 - mdpi.com
The great mechanical properties, biocompatibility and biodegradability of silk-based
materials make them applicable to the biomedical field. Genetic engineering enables the …
materials make them applicable to the biomedical field. Genetic engineering enables the …
Bioactivation of spider silk with basic fibroblast growth factor for in vitro cell culture: A step toward creation of artificial ECM
N Thatikonda, L Nilebäck, A Kempe… - ACS Biomaterials …, 2018 - ACS Publications
Presentation of immobilized growth factors with retained bioactivity remains a challenge in
the field of tissue engineering. In the present study, we propose a strategy to covalently …
the field of tissue engineering. In the present study, we propose a strategy to covalently …
Genetically engineered mucoadhesive spider silk
G Petrou, R Jansson, M Högqvist… - …, 2018 - ACS Publications
Mucoadhesion is defined as the adhesion of a material to the mucus gel covering the
mucous membranes. The mechanisms controlling mucoadhesion include nonspecific …
mucous membranes. The mechanisms controlling mucoadhesion include nonspecific …