Endothelial dysfunction and hypertension

D Konukoglu, H Uzun - Hypertension: from basic research to clinical …, 2017 - Springer
In the past, endothelium was thought to be only a mechanical barrier. Today, endothelium is
known to be a tissue regulating vascular tone, cell growth and the interaction between the …

Nutrients and oxidative stress: friend or foe?

BL Tan, ME Norhaizan… - Oxidative medicine and …, 2018 - Wiley Online Library
There are different types of nutritionally mediated oxidative stress sources that trigger
inflammation. Much information indicates that high intakes of macronutrients can promote …

Evaluation of oxidative stress in biological samples using the thiobarbituric acid reactive substances assay

JAD De Leon, CR Borges - Journal of visualized experiments …, 2020 - pmc.ncbi.nlm.nih.gov
Despite its limited analytical specificity and ruggedness, the thiobarbituric acid reactive
substances (TBARS) assay has been widely used as a generic metric of lipid peroxidation in …

Detecting human coronary inflammation by imaging perivascular fat

AS Antonopoulos, F Sanna, N Sabharwal… - Science translational …, 2017 - science.org
Early detection of vascular inflammation would allow deployment of targeted strategies for
the prevention or treatment of multiple disease states. Because vascular inflammation is not …

Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine

H Ibrahim, A Perl, D Smith, T Lewis, Z Kon… - Clinical …, 2020 - Elsevier
Abstract Glucose 6-phosphate dehydrogenase (G6PD) deficiency facilitates human
coronavirus infection due to glutathione depletion. G6PD deficiency may especially …

Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal

A Ayala, MF Muñoz, S Argüelles - Oxidative medicine and …, 2014 - Wiley Online Library
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …

Mechanisms, consequences, and prevention of coronary graft failure

M Gaudino, C Antoniades, U Benedetto, S Deb… - Circulation, 2017 - Am Heart Assoc
Graft failure occurs in a sizeable proportion of coronary artery bypass conduits. We herein
review relevant current evidence to give an overview of the incidence, pathophysiology, and …

Oxidative stress, antioxidants and hypertension

M Amponsah-Offeh, P Diaba-Nuhoho, S Speier… - Antioxidants, 2023 - mdpi.com
As a major cause of morbidity and mortality globally, hypertension remains a serious threat
to global public health. Despite the availability of many antihypertensive medications …

[HTML][HTML] Biological markers of oxidative stress: applications to cardiovascular research and practice

E Ho, KK Galougahi, CC Liu, R Bhindi, GA Figtree - Redox biology, 2013 - Elsevier
Oxidative stress is a common mediator in pathogenicity of established cardiovascular risk
factors. Furthermore, it likely mediates effects of emerging, less well-defined variables that …

Oxidative stress and human hypertension: vascular mechanisms, biomarkers, and novel therapies

AC Montezano, M Dulak-Lis, S Tsiropoulou… - Canadian Journal of …, 2015 - Elsevier
Hypertension is a major cardiovascular risk factor. Of the many processes involved in the
pathophysiology of hypertension, vascular damage due to oxidative stress (excess …