Endothelial dysfunction and hypertension
In the past, endothelium was thought to be only a mechanical barrier. Today, endothelium is
known to be a tissue regulating vascular tone, cell growth and the interaction between the …
known to be a tissue regulating vascular tone, cell growth and the interaction between the …
Nutrients and oxidative stress: friend or foe?
There are different types of nutritionally mediated oxidative stress sources that trigger
inflammation. Much information indicates that high intakes of macronutrients can promote …
inflammation. Much information indicates that high intakes of macronutrients can promote …
Evaluation of oxidative stress in biological samples using the thiobarbituric acid reactive substances assay
Despite its limited analytical specificity and ruggedness, the thiobarbituric acid reactive
substances (TBARS) assay has been widely used as a generic metric of lipid peroxidation in …
substances (TBARS) assay has been widely used as a generic metric of lipid peroxidation in …
Detecting human coronary inflammation by imaging perivascular fat
AS Antonopoulos, F Sanna, N Sabharwal… - Science translational …, 2017 - science.org
Early detection of vascular inflammation would allow deployment of targeted strategies for
the prevention or treatment of multiple disease states. Because vascular inflammation is not …
the prevention or treatment of multiple disease states. Because vascular inflammation is not …
Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine
H Ibrahim, A Perl, D Smith, T Lewis, Z Kon… - Clinical …, 2020 - Elsevier
Abstract Glucose 6-phosphate dehydrogenase (G6PD) deficiency facilitates human
coronavirus infection due to glutathione depletion. G6PD deficiency may especially …
coronavirus infection due to glutathione depletion. G6PD deficiency may especially …
Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4‐hydroxy‐2‐nonenal
Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
free radicals attack lipids containing carbon‐carbon double bond (s), especially …
Mechanisms, consequences, and prevention of coronary graft failure
Graft failure occurs in a sizeable proportion of coronary artery bypass conduits. We herein
review relevant current evidence to give an overview of the incidence, pathophysiology, and …
review relevant current evidence to give an overview of the incidence, pathophysiology, and …
Oxidative stress, antioxidants and hypertension
M Amponsah-Offeh, P Diaba-Nuhoho, S Speier… - Antioxidants, 2023 - mdpi.com
As a major cause of morbidity and mortality globally, hypertension remains a serious threat
to global public health. Despite the availability of many antihypertensive medications …
to global public health. Despite the availability of many antihypertensive medications …
[HTML][HTML] Biological markers of oxidative stress: applications to cardiovascular research and practice
Oxidative stress is a common mediator in pathogenicity of established cardiovascular risk
factors. Furthermore, it likely mediates effects of emerging, less well-defined variables that …
factors. Furthermore, it likely mediates effects of emerging, less well-defined variables that …
Oxidative stress and human hypertension: vascular mechanisms, biomarkers, and novel therapies
AC Montezano, M Dulak-Lis, S Tsiropoulou… - Canadian Journal of …, 2015 - Elsevier
Hypertension is a major cardiovascular risk factor. Of the many processes involved in the
pathophysiology of hypertension, vascular damage due to oxidative stress (excess …
pathophysiology of hypertension, vascular damage due to oxidative stress (excess …