Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders

LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …

Exposure to air pollution in relation to risk of dementia and related outcomes: an updated systematic review of the epidemiological literature

J Weuve, EE Bennett, L Ranker… - Environmental …, 2021 - ehp.niehs.nih.gov
Background: Dementia is a devastating neurologic condition that is common in older adults.
We previously reviewed the epidemiological evidence examining the hypothesis that long …

[HTML][HTML] A critical review of the epidemiological evidence of effects of air pollution on dementia, cognitive function and cognitive decline in adult population

JM Delgado-Saborit, V Guercio, AM Gowers… - Science of the Total …, 2021 - Elsevier
Dementia is arguably the most pressing public health challenge of our age. Since dementia
does not have a cure, identifying risk factors that can be controlled has become paramount …

A review of the possible associations between ambient PM2. 5 exposures and the development of Alzheimer's disease

Y Shou, Y Huang, X Zhu, C Liu, Y Hu… - … and Environmental Safety, 2019 - Elsevier
PM2. 5 particles in air pollution have been widely considered associated with respiratory
and cardiovascular diseases. Recent studies have shown that PM2. 5 can also cause …

[HTML][HTML] Pathophysiologic relationship between Alzheimer's disease, cerebrovascular disease, and cardiovascular risk: a review and synthesis

CY Santos, PJ Snyder, WC Wu, M Zhang… - Alzheimer's & Dementia …, 2017 - Elsevier
As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …

[HTML][HTML] Exposure to ambient air pollution and the incidence of dementia: a population-based cohort study

H Chen, JC Kwong, R Copes, P Hystad… - Environment …, 2017 - Elsevier
Introduction Emerging studies have implicated air pollution in the neurodegenerative
processes. Less is known about the influence of air pollution, especially at the relatively low …

Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models

M Cacciottolo, X Wang, I Driscoll, N Woodward… - Translational …, 2017 - nature.com
Exposure to particulate matter (PM) in the ambient air and its interactions with APOE alleles
may contribute to the acceleration of brain aging and the pathogenesis of Alzheimer's …

Are noise and air pollution related to the incidence of dementia? A cohort study in London, England

IM Carey, HR Anderson, RW Atkinson, SD Beevers… - BMJ open, 2018 - bmjopen.bmj.com
Objective To investigate whether the incidence of dementia is related to residential levels of
air and noise pollution in London. Design Retrospective cohort study using primary care …

Environmental risk factors for dementia: a systematic review

LOJ Killin, JM Starr, IJ Shiue, TC Russ - BMC geriatrics, 2016 - Springer
Background Dementia risk reduction is a major and growing public health priority. While
certain modifiable risk factors for dementia have been identified, there remains a substantial …

Olfactory dysfunction in neurodegenerative diseases: is there a common pathological substrate?

RL Doty - The Lancet Neurology, 2017 - thelancet.com
In patients with neurodegenerative diseases, there is a spectrum of smell dysfunction
ranging from severe loss, as seen in Alzheimer's disease and Parkinson's disease, to …