Vasculature-on-a-chip for in vitro disease models
Vascularization, the formation of new blood vessels, is an essential biological process. As
the vasculature is involved in various fundamental physiological phenomena and closely …
the vasculature is involved in various fundamental physiological phenomena and closely …
Tissue‐Engineered Microvessels: A Review of Current Engineering Strategies and Applications
Microvessels, including arterioles, capillaries, and venules, play an important role in
regulating blood flow, enabling nutrient and waste exchange, and facilitating immune …
regulating blood flow, enabling nutrient and waste exchange, and facilitating immune …
3D microvascularized tissue models by laser‐based cavitation molding of collagen
Abstract 3D tissue models recapitulating human physiology are important for fundamental
biomedical research, and they hold promise to become a new tool in drug development. An …
biomedical research, and they hold promise to become a new tool in drug development. An …
Engineered 3D vascular and neuronal networks in a microfluidic platform
Neurovascular coupling plays a key role in the pathogenesis of neurodegenerative
disorders including motor neuron disease (MND). In vitro models provide an opportunity to …
disorders including motor neuron disease (MND). In vitro models provide an opportunity to …
A new microfluidic model that allows monitoring of complex vascular structures and cell interactions in a 3D biological matrix
CGM van Dijk, MM Brandt, N Poulis, J Anten… - Lab on a Chip, 2020 - pubs.rsc.org
Microfluidic organ-on-a-chip designs are used to mimic human tissues, including the
vasculature. Here we present a novel microfluidic device that allows the interaction of …
vasculature. Here we present a novel microfluidic device that allows the interaction of …
[HTML][HTML] Integrating engineered macro vessels with self-assembled capillaries in 3D implantable tissue for promoting vascular integration in-vivo
A functional multi-scale vascular network can promote 3D engineered tissue growth and
improve transplantation outcome. In this work, by using a combination of living cells …
improve transplantation outcome. In this work, by using a combination of living cells …
Channels in a porous scaffold: a new player for vascularization
Vascularization is essential for tissue regeneration. Despite extensive efforts in the past
decades, sufficient and rapid vascularization remains a major challenge in tissue …
decades, sufficient and rapid vascularization remains a major challenge in tissue …
Crosstalk between develo** vasculature and optogenetically engineered skeletal muscle improves muscle contraction and angiogenesis
Capillary networks surrounding skeletal muscle play an important role in not only supplying
oxygen and nutrients but also in regulating the myogenesis and repair of skeletal muscle …
oxygen and nutrients but also in regulating the myogenesis and repair of skeletal muscle …
[HTML][HTML] Multi-organ-on-chip approach in cancer research
A Zuchowska, S Skorupska - Organs-on-a-Chip, 2022 - Elsevier
Cancer is the second cause of death worldwide after heart disease. Despite the still
develo** anticancer therapies, the main challenge in cancer research is the establishing …
develo** anticancer therapies, the main challenge in cancer research is the establishing …
Lymphangion-chip: a microphysiological system which supports co-culture and bidirectional signaling of lymphatic endothelial and muscle cells
The pathophysiology of several lymphatic diseases, such as lymphedema, depends on the
function of lymphangions that drive lymph flow. Even though the signaling between the two …
function of lymphangions that drive lymph flow. Even though the signaling between the two …