Keratin expression in human tissues and neoplasms Keratin filaments constitute type I and
type II intermediate filaments (IFs), with at least 20 subtypes named keratin 1–20. Since …

Immunohistochemistry plays an indispensable role in accurate diagnosis of malignant
mesothelioma, particularly in morphologically challenging cases and in biopsy and cytology …

Refer all patients with a chest X-ray suggestive of MPM urgently (via the 2-week wait
suspected cancer pathway in England and Wales). Consider referral for further investigation …

The availability of targeted therapies has created a need for precise subty** of non-small
cell lung carcinomas (NSCLCs). The aim of this study was to assess the utility of …

A large number of immunohistochemical markers that can facilitate the distinction between
epithelioid pleural mesotheliomas and pulmonary peripheral adenocarcinomas have …

Mesothelin is a cell surface antigen of unknown function that is strongly expressed in
mesothelial cells. Although it was reported in 1992 that immunostaining with the K1 anti …

Abstract Context.—“Undifferentiated tumor” refers to a heterogeneous group of neoplasms
with little or no evidence of differentiation on routine light microscopic morphology …

Podoplanin is a specific marker for lymph vessel endothelial cells. It was noted that
podoplanin is expressed in reactive mesothelial cells. The utility of podoplanin for the …

We evaluated the sensitivity and specificity of 10 monoclonal and two polyclonal antibodies
for distinguishing epithelioid mesothelioma from adenocarcinoma (AdCA) using …

This study was aimed to evaluate the utility of a panel of antibodies, consisting of thyroid
transcription factor-1 (TTF-1), p63, and cytokeratins (CK) 5/6 for distinguishing between …