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Development and arealization of the cerebral cortex
Adult cortical areas consist of specialized cell types and circuits that support unique higher-
order cognitive functions. How this regional diversity develops from an initially uniform …
order cognitive functions. How this regional diversity develops from an initially uniform …
Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex
Cortical circuits are composed predominantly of pyramidal-to-pyramidal neuron
connections, yet their assembly during embryonic development is not well understood. We …
connections, yet their assembly during embryonic development is not well understood. We …
Human assembloids reveal the consequences of CACNA1G gene variants in the thalamocortical pathway
Abnormalities in thalamocortical crosstalk can lead to neuropsychiatric disorders. Variants in
CACNA1G, which encodes the α1G subunit of the thalamus-enriched T-type calcium …
CACNA1G, which encodes the α1G subunit of the thalamus-enriched T-type calcium …
Activity-dependent death of transient Cajal-Retzius neurons is required for functional cortical wiring
M Riva, I Genescu, C Habermacher, D Orduz… - elife, 2019 - elifesciences.org
Programmed cell death and early activity contribute to the emergence of functional cortical
circuits. While most neuronal populations are scaled-down by death, some subpopulations …
circuits. While most neuronal populations are scaled-down by death, some subpopulations …
[HTML][HTML] Dynamic interplay between thalamic activity and Cajal-Retzius cells regulates the wiring of cortical layer 1
Cortical wiring relies on guidepost cells and activity-dependent processes that are thought to
act sequentially. Here, we show that the construction of layer 1 (L1), a main site of top-down …
act sequentially. Here, we show that the construction of layer 1 (L1), a main site of top-down …
[HTML][HTML] Heterogeneity in oligodendrocyte precursor cell proliferation is dynamic and driven by passive bioelectrical properties
H Pivoňková, S Sitnikov, Y Kamen, A Vanhaesebrouck… - Cell Reports, 2024 - cell.com
Oligodendrocyte precursor cells (OPCs) generate myelinating oligodendrocytes and are the
main proliferative cells in the adult central nervous system. OPCs are a heterogeneous …
main proliferative cells in the adult central nervous system. OPCs are a heterogeneous …
Supplemental information for Dynamic interplay between thalamic activity and Cajal-Retzius cells regulates the wiring of cortical layer 1
I Genescu, M Aníbal-Martínez, V Kouskoff… - 2022 - digital.csic.es
Cortical wiring relies on guidepost cells and activity-dependent processes that are thought to
act sequentially. Here, we show that the construction of layer 1 (L1), a main site of top-down …
act sequentially. Here, we show that the construction of layer 1 (L1), a main site of top-down …