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Mesenchymal stem cell-based therapy for cardiovascular disease: progress and challenges
Administration of mesenchymal stem cells (MSCs) to diseased hearts improves cardiac
function and reduces scar. These effects occur via stimulation of endogenous repair …
function and reduces scar. These effects occur via stimulation of endogenous repair …
[HTML][HTML] Mesenchymal stem cell secretome as an emerging cell-free alternative for improving wound repair
The use of mesenchymal stem cells (MSC) for the treatment of cutaneous wounds is
currently of enormous interest. However, the broad translation of cell therapies into clinical …
currently of enormous interest. However, the broad translation of cell therapies into clinical …
3D printed complex tissue construct using stem cell-laden decellularized extracellular matrix bioinks for cardiac repair
Stem cell therapy is a promising therapeutic method for the treatment of ischemic heart
diseases; however, some challenges prohibit the efficacy after cell delivery due to hostile …
diseases; however, some challenges prohibit the efficacy after cell delivery due to hostile …
Physiological implications of myocardial scar structure
Once myocardium dies during a heart attack, it is replaced by scar tissue over the course of
several weeks. The size, location, composition, structure and mechanical properties of the …
several weeks. The size, location, composition, structure and mechanical properties of the …
Proangiogenic features of mesenchymal stem cells and their therapeutic applications
Mesenchymal stem cells (MSCs) have shown their therapeutic potency for treatment of
cardiovascular diseases owing to their low immunogenicity, ease of isolation and …
cardiovascular diseases owing to their low immunogenicity, ease of isolation and …
A viscoelastic adhesive epicardial patch for treating myocardial infarction
Acellular epicardial patches that treat myocardial infarction by increasing the mechanical
integrity of damaged left ventricular tissues exhibit widely scattered therapeutic efficacy …
integrity of damaged left ventricular tissues exhibit widely scattered therapeutic efficacy …
Cardiac fibrosis: potential therapeutic targets
S Park, NB Nguyen, A Pezhouman, R Ardehali - Translational Research, 2019 - Elsevier
Cardiovascular disease is a leading cause of mortality in the world and is exacerbated by
the presence of cardiac fibrosis, defined by the accumulation of noncontractile extracellular …
the presence of cardiac fibrosis, defined by the accumulation of noncontractile extracellular …
Enhancement of mesenchymal stem cell angiogenic capacity and stemness by a biomimetic hydrogel scaffold
KC Rustad, VW Wong, M Sorkin, JP Glotzbach… - Biomaterials, 2012 - Elsevier
In this study, we examined the capacity of a biomimetic pullulan–collagen hydrogel to create
a functional biomaterial-based stem cell niche for the delivery of mesenchymal stem cells …
a functional biomaterial-based stem cell niche for the delivery of mesenchymal stem cells …
Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue
KR Stevens, KL Kreutziger, SK Dupras… - Proceedings of the …, 2009 - pnas.org
Success of human myocardial tissue engineering for cardiac repair has been limited by
adverse effects of scaffold materials, necrosis at the tissue core, and poor survival after …
adverse effects of scaffold materials, necrosis at the tissue core, and poor survival after …
[HTML][HTML] Drug and cell delivery for cardiac regeneration
CL Hastings, ET Roche, E Ruiz-Hernandez… - Advanced drug delivery …, 2015 - Elsevier
The spectrum of ischaemic cardiomyopathy, encompassing acute myocardial infarction to
congestive heart failure is a significant clinical issue in the modern era. This group of …
congestive heart failure is a significant clinical issue in the modern era. This group of …