[HTML][HTML] Rare ginsenosides: A unique perspective of ginseng research

W Fan, L Fan, Z Wang, Y Mei, L Liu, L Li, L Yang… - Journal of Advanced …, 2024 - Elsevier
Abstract Background Rare ginsenosides (Rg3, Rh2, CK, etc.) refer to a group of dammarane
triterpenoids that exist in low natural abundance, mostly produced by deglycosylation or side …

Biotransformation of ginsenosides by hydrolyzing the sugar moieties of ginsenosides using microbial glycosidases

CS Park, MH Yoo, KH Noh, DK Oh - Applied microbiology and …, 2010 - Springer
Ginsenosides are the principal components responsible for the pharmaceutical activities of
ginseng. The minor ginsenosides, which are also pharmaceutically active, can be produced …

Production of bioactive ginsenosides Rh2 and Rg3 by metabolically engineered yeasts

P Wang, Y Wei, Y Fan, Q Liu, W Wei, C Yang… - Metabolic …, 2015 - Elsevier
Abstract Ginsenosides Rh2 and Rg3 represent promising candidates for cancer prevention
and therapy and have low toxicity. However, the concentrations of Rh2 and Rg3 are …

Ginsenoside Rb1 as a neuroprotective agent: A review

T Ahmed, SH Raza, A Maryam, WN Setzer… - Brain research …, 2016 - Elsevier
Ginsenosides represent the major bioactive components of ginseng. These triterpenoid
saponins have been shown to exert numerous beneficial effects on the human body. Recent …

Simultaneous quantification of 19 ginsenosides in black ginseng developed from Panax ginseng by HPLC–ELSD

BS Sun, LJ Gu, ZM Fang, C Wang, Z Wang… - … of pharmaceutical and …, 2009 - Elsevier
A high-performance liquid chromatographic method with evaporative light scattering
detection (HPLC–ELSD) has been developed to identify and quantify 19 ginsenosides (Rg1 …

[HTML][HTML] Microbial biotransformation as a tool for drug development based on natural products from mevalonic acid pathway: A review

MEF Hegazy, TA Mohamed, AI ElShamy… - Journal of Advanced …, 2015 - Elsevier
Natural products are structurally and biologically interesting metabolites, but they have been
isolated in minute amounts. The syntheses of such natural products help in obtaining them …

Anti-angiogenic properties of ginsenoside Rg3

M Nakhjavani, E Smith, AR Townsend, TJ Price… - Molecules, 2020 - mdpi.com
Ginsenoside Rg3 (Rg3) is a member of the ginsenoside family of chemicals extracted from
Panax ginseng. Like other ginsenosides, Rg3 has two epimers: 20 (S)-ginsenoside Rg3 …

Production and pharmaceutical research of minor saponins in Panax notoginseng (Sanqi): Current status and future prospects

H Zhang, J Li, M Diao, J Li, N **e - Phytochemistry, 2024 - Elsevier
ABSTRACT Panax notoginseng (Burk.) FH Chen is a traditional medicinal herb known as
Sanqi or Tianqi in Asia and is commonly used worldwide. It is one of the main raw …

A mechanism of glucose tolerance and stimulation of GH1 β-glucosidases

Y Yang, X Zhang, Q Yin, W Fang, Z Fang, X Wang… - Scientific reports, 2015 - nature.com
Abstract β-Glucosidases are enzymes that hydrolyze β-glycosidic bonds to release non-
reducing terminal glucosyl residues from glycosides and oligosaccharides and thus have …

β-Glucosidase and Its Application in Bioconversion of Ginsenosides in Panax ginseng

TNA Tran, JS Son, M Awais, JH Ko, DC Yang, SK Jung - Bioengineering, 2023 - mdpi.com
Ginsenosides are a group of bioactive compounds isolated from Panax ginseng.
Conventional major ginsenosides have a long history of use in traditional medicine for both …