Structure, function, and mechanism of the nickel metalloenzymes, CO dehydrogenase, and acetyl-CoA synthase

M Can, FA Armstrong, SW Ragsdale - Chemical reviews, 2014 - ACS Publications
1.1. Research on Catalytic Reactions Involving CO and CO2: Relationship to Energy, the
Environment, Biogeochemistry, Toxicology, Health, and Technology The major …

Engineering microbial consortia by division of labor

GW Roell, J Zha, RR Carr, MA Koffas, SS Fong… - Microbial cell …, 2019 - Springer
During microbial applications, metabolic burdens can lead to a significant drop in cell
performance. Novel synthetic biology tools or multi-step bioprocessing (eg, fermentation …

An atlas of human metabolism

JL Robinson, P Kocabaş, H Wang, PE Cholley… - Science …, 2020 - science.org
Genome-scale metabolic models (GEMs) are valuable tools to study metabolism and
provide a scaffold for the integrative analysis of omics data. Researchers have developed …

21st century natural product research and drug development and traditional medicines

LT Ngo, JI Okogun, WR Folk - Natural product reports, 2013 - pubs.rsc.org
Covering: 1987 to 2013 Natural products and related structures are essential sources of new
pharmaceuticals, because of the immense variety of functionally relevant secondary …

Zea mays iRS1563: A Comprehensive Genome-Scale Metabolic Reconstruction of Maize Metabolism

R Saha, PF Suthers, CD Maranas - PloS one, 2011 - journals.plos.org
The scope and breadth of genome-scale metabolic reconstructions have continued to
expand over the last decade. Herein, we introduce a genome-scale model for a plant with …

Metabolic network modeling of microbial interactions in natural and engineered environmental systems

O Perez-Garcia, G Lear, N Singhal - Frontiers in microbiology, 2016 - frontiersin.org
We review approaches to characterize metabolic interactions within microbial communities
using Stoichiometric Metabolic Network (SMN) models for applications in environmental and …

A reliable simulator for dynamic flux balance analysis

K Höffner, SM Harwood… - Biotechnology and …, 2013 - Wiley Online Library
Dynamic flux balance analysis (DFBA) provides a platform for detailed design, control and
optimization of biochemical process technologies. It is a promising modeling framework that …

Engineering of microorganisms for the production of biofuels and perspectives based on systems metabolic engineering approaches

YS Jang, JM Park, S Choi, YJ Choi, JH Cho… - Biotechnology …, 2012 - Elsevier
The increasing oil price and environmental concerns caused by the use of fossil fuel have
renewed our interest in utilizing biomass as a sustainable resource for the production of …

Emergent biosynthetic capacity in simple microbial communities

HC Chiu, R Levy, E Borenstein - PLOS computational biology, 2014 - journals.plos.org
Microbes have an astonishing capacity to transform their environments. Yet, the metabolic
capacity of a single species is limited and the vast majority of microorganisms form complex …

Comparative analysis of yeast metabolic network models highlights progress, opportunities for metabolic reconstruction

BD Heavner, ND Price - PLoS computational biology, 2015 - journals.plos.org
We have compared 12 genome-scale models of the Saccharomyces cerevisiae metabolic
network published since 2003 to evaluate progress in reconstruction of the yeast metabolic …