Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration

H Wei, J Cui, K Lin, J **e, X Wang - Bone research, 2022 - nature.com
Bone defects combined with tumors, infections, or other bone diseases are challenging in
clinical practice. Autologous and allogeneic grafts are two main traditional remedies, but …

Design, printing, and engineering of regenerative biomaterials for personalized bone healthcare

Z Jia, X Xu, D Zhu, Y Zheng - Progress in Materials Science, 2023 - Elsevier
Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

[HTML][HTML] Advanced surface engineering of titanium materials for biomedical applications: From static modification to dynamic responsive regulation

P Jiang, Y Zhang, R Hu, B Shi, L Zhang, Q Huang… - Bioactive Materials, 2023 - Elsevier
Titanium (Ti) and its alloys have been widely used as orthopedic implants, because of their
favorable mechanical properties, corrosion resistance and biocompatibility. Despite their …

Bone repair biomaterials: a perspective from immunomodulation

Y Wang, H Zhang, Y Hu, Y **g… - Advanced Functional …, 2022 - Wiley Online Library
With an increasingly aging society, bone defects and fractures have become significant
threats to human health and quality of life. Currently, autologous and allogeneic bone grafts …

Biomimetic glycopeptide hydrogel coated PCL/nHA scaffold for enhanced cranial bone regeneration via macrophage M2 polarization-induced osteo …

Y Wang, J Wang, R Gao, X Liu, Z Feng, C Zhang… - Biomaterials, 2022 - Elsevier
The reconstruction of large cranial bone defects by bioactive materials without exogenous
cells or growth factors remains a substantial clinical challenge. Here, synthetic fibrous …

A review of 3D polymeric scaffolds for bone tissue engineering: principles, fabrication techniques, immunomodulatory roles, and challenges

AG Abdelaziz, H Nageh, SM Abdo, MS Abdalla… - Bioengineering, 2023 - mdpi.com
Over the last few years, biopolymers have attracted great interest in tissue engineering and
regenerative medicine due to the great diversity of their chemical, mechanical, and physical …

Regulation of macrophage polarization through surface topography design to facilitate implant-to-bone osteointegration

Y Zhu, H Liang, X Liu, J Wu, C Yang, TM Wong… - Science …, 2021 - science.org
Proper immune responses are critical for successful biomaterial implantation. Here, four
scales of honeycomb-like TiO2 structures were custom made on titanium (Ti) substrates to …

Biodegradable magnesium‐based implants in orthopedics—a general review and perspectives

JL Wang, JK Xu, C Hopkins, DHK Chow… - Advanced …, 2020 - Wiley Online Library
Biodegradable Mg‐based metals may be promising orthopedic implants for treating
challenging bone diseases, attributed to their desirable mechanical and osteopromotive …

Multiscale architecture design of 3D printed biodegradable Zn-based porous scaffolds for immunomodulatory osteogenesis

S Li, H Yang, X Qu, Y Qin, A Liu, G Bao… - Nature …, 2024 - nature.com
Reconciling the dilemma between rapid degradation and overdose toxicity is challenging in
biodegradable materials when shifting from bulk to porous materials. Here, we achieve …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …