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ICAM-1: A master regulator of cellular responses in inflammation, injury resolution, and tumorigenesis
ICAM-1 is a cell surface glycoprotein and an adhesion receptor that is best known for
regulating leukocyte recruitment from circulation to sites of inflammation. However, in …
regulating leukocyte recruitment from circulation to sites of inflammation. However, in …
Lymphatic vessel network structure and physiology
The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …
which has the holistic function to maintain the local physiologic environment for every cell in …
Immune cell trafficking across the blood-brain barrier in the absence and presence of neuroinflammation
To maintain the homeostatic environment required for proper function of central nervous
system (CNS) neurons the endothelial cells of CNS microvessels tightly regulate the …
system (CNS) neurons the endothelial cells of CNS microvessels tightly regulate the …
Intercellular adhesion molecule 1: more than a leukocyte adhesion molecule
CD Haydinger, LM Ashander, ACR Tan, JR Smith - Biology, 2023 - mdpi.com
Simple Summary Intercellular adhesion molecule 1 (ICAM-1) is a protein produced by cells
in blood vessel walls, as well as many other cell types. It localizes to the surface of these …
in blood vessel walls, as well as many other cell types. It localizes to the surface of these …
A central role for inflammation in the pathogenesis of diabetic retinopathy
AM Joussen, V Poulaki, ML Le, K Koizumi… - The FASEB …, 2004 - Wiley Online Library
Diabetic retinopathy is a leading cause of adult vision loss and blindness. Much of the retinal
damage that characterizes the disease results from retinal vascular leakage and …
damage that characterizes the disease results from retinal vascular leakage and …
A major role for VCAM-1, but not ICAM-1, in early atherosclerosis
MI Cybulsky, K Iiyama, H Li, S Zhu, M Chen… - The Journal of clinical …, 2001 - jci.org
VCAM-1 and ICAM-1 are endothelial adhesion molecules of the Ig gene superfamily that
may participate in atherogenesis by promoting monocyte accumulation in the arterial intima …
may participate in atherogenesis by promoting monocyte accumulation in the arterial intima …
[HTML][HTML] Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke
Each year about 650,000 Europeans die from stroke and a similar number lives with the
sequelae of multiple sclerosis (MS). Stroke and MS differ in their etiology. Although cause …
sequelae of multiple sclerosis (MS). Stroke and MS differ in their etiology. Although cause …
[HTML][HTML] Neutrophils: molecules, functions and pathophysiological aspects
V Witko-Sarsat, P Rieu, B Descamps-Latscha… - Laboratory …, 2000 - Elsevier
CONCLUSION The notion that inflammation is the net resultant of pro and contra
inflammatory pathways (Fauve, 1980) is well illustrated by the dual role of neutrophils which …
inflammatory pathways (Fauve, 1980) is well illustrated by the dual role of neutrophils which …
Cellular and molecular functions of hepatic stellate cells in inflammatory responses and liver immunology
The liver is a central immunological organ. Liver resident macrophages, Kupffer cells (KC),
but also sinusoidal endothelial cells, dendritic cells (DC) and other immune cells are …
but also sinusoidal endothelial cells, dendritic cells (DC) and other immune cells are …
Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1–deficient mice
Summary Monocyte chemoattractant protein 1 (MCP-1) is a CC chemokine that attracts
monocytes, memory T lymphocytes, and natural killer cells. Because other chemokines have …
monocytes, memory T lymphocytes, and natural killer cells. Because other chemokines have …