There is increasing awareness that epistasis or gene-gene interaction plays a role in
susceptibility to common human diseases. In this paper, we formulate a working hypothesis …

Evolutionary genetics has recently made enormous progress in understanding how genetic
variation maps into phenotypic variation. However, why some traits are phenotypically …

Over the past decade, advances in both molecular developmental biology and evolutionary
ecology have made possible a new understanding of organisms as dynamic systems …

Beim Studium der jüngeren Kontroversen über den Darwinismus fiel mir wiederholt auf, das
sie falsche Darstellungen enthielten, so als würde es sich um irgendetwas Umfassenderes …

The widespread availability of high-throughput genoty** technology has opened the door
to the era of personal genetics, which brings to consumers the promise of using genetic …

Epistatic gene interactions are believed to be a major factor in the genetic architecture of
evolutionary diversification. In Arabidopsis thaliana, the FRI and FLC genes mechanistically …

Quantitative genetics traces its roots back through more than a century of theory, largely
formed in the absence of directly observable genotype data, and has remained essentially …

Interaction between genes, or epistasis, is found to be common and it is a key concept for
understanding adaptation and evolution of natural populations, response to selection in …

Co-evolution has produced many intriguing adaptations and made significant contributions
to biodiversity through the co-adaptive radiations of interacting groups, such as pollinating …

The fitness effects of a mutation can depend, sometimes dramatically, on genetic
background; this phenomenon is often referred to as “epistasis.” Epistasis can have …