Neuronal voltage-gated calcium channels: structure, function, and dysfunction
BA Simms, GW Zamponi - Neuron, 2014 - cell.com
Voltage-gated calcium channels are the primary mediators of depolarization-induced
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …
Presynaptic calcium channels: specialized control of synaptic neurotransmitter release
Chemical synapses are heterogeneous junctions formed between neurons that are
specialized for the conversion of electrical impulses into the exocytotic release of …
specialized for the conversion of electrical impulses into the exocytotic release of …
Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error
Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …
increasingly common cause of blindness. This genome-wide association meta-analysis in …
Auditory neuropathy—neural and synaptic mechanisms
Sensorineural hearing impairment is the most common form of hearing loss, and
encompasses pathologies of the cochlea and the auditory nerve. Hearing impairment …
encompasses pathologies of the cochlea and the auditory nerve. Hearing impairment …
[HTML][HTML] Retinal remodeling in human retinitis pigmentosa
Retinitis Pigmentosa (RP) in the human is a progressive, currently irreversible neural
degenerative disease usually caused by gene defects that disrupt the function or …
degenerative disease usually caused by gene defects that disrupt the function or …
Congenital stationary night blindness: an analysis and update of genotype–phenotype correlations and pathogenic mechanisms
C Zeitz, AG Robson, I Audo - Progress in retinal and eye research, 2015 - Elsevier
Congenital stationary night blindness (CSNB) refers to a group of genetically and clinically
heterogeneous retinal disorders. Seventeen different genes with more than 360 different …
heterogeneous retinal disorders. Seventeen different genes with more than 360 different …
Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling
RD Burgoyne - Nature Reviews Neuroscience, 2007 - nature.com
In neurons, intracellular calcium signals have crucial roles in activating neurotransmitter
release and in triggering alterations in neuronal function. Calmodulin has been widely …
release and in triggering alterations in neuronal function. Calmodulin has been widely …
Biology and therapy of inherited retinal degenerative disease: insights from mouse models
S Veleri, CH Lazar, B Chang… - Disease models & …, 2015 - journals.biologists.com
Retinal neurodegeneration associated with the dysfunction or death of photoreceptors is a
major cause of incurable vision loss. Tremendous progress has been made over the last two …
major cause of incurable vision loss. Tremendous progress has been made over the last two …
The diverse roles of ribbon synapses in sensory neurotransmission
G Matthews, P Fuchs - Nature Reviews Neuroscience, 2010 - nature.com
Sensory synapses of the visual and auditory systems must faithfully encode a wide dynamic
range of graded signals, and must be capable of sustained transmitter release over long …
range of graded signals, and must be capable of sustained transmitter release over long …
Voltage-gated calcium channels: key players in sensory coding in the retina and the inner ear
Calcium influx through voltage-gated Ca (CaV) channels is the first step in synaptic
transmission. This review concerns CaV channels at ribbon synapses in primary sense …
transmission. This review concerns CaV channels at ribbon synapses in primary sense …