Brain ischemia is one of the principal causes of death and disability worldwide in which
prevention or an effective treatment does not exist. In order to develop successful treatments …

This study investigated the effects of cannabidiol (CBD), a non-psychotomimetic
phytochemical present in Cannabis sativa, on the cognitive and emotional impairments …

The aim of this study was to examine the comprehensive neuroprotective mechanism of
ligustrazine, which is extracted from Ligusticum Chuanxiong Hort., against vascular …

Stroke is a life-threatening medical condition and is a leading cause of disability. Cerebral
ischemia is characterized by a distinct inflammatory response starting with the production of …

Adult neurogenesis is thought to be crucial for preserving cognitive functions, which is tightly
controlled by various epigenetic regulators. As the methyltransferase of histone H3K27, the …

Depression and anxiety have been reported as the major neuropsychiatric consequences
following stroke. Minocycline, a neuroprotective drug has minimized depressive symptoms …

Abstract Astragaloside IV (AS-IV) is the main active component isolated from the traditional
Chinese medicinal herb Astragalus membranaceus. Studies have demonstrated that AS-IV …

Vascular cognitive impairment (VCI) is a common sequela of cerebrovascular disorders.
Although transcutaneous auricular vagus nerve stimulation (taVNS) has been considered a …

The present study investigated whether cannabidiol (CBD), a major non-psychoactive
constituent of marijuana, protects against hippocampal neurodegeneration and cognitive …

Abstract Aquaporin-4 (AQP4), the principal water channel in astrocytes, is involved in brain
water movement, inflammation, and neuroexcitation. In this study, there was strong …