Expression of proteins inside cells is noisy, causing variability in protein concentration
among identical cells. A central problem in cellular control is how cells cope with this …

Through the comparison between two major, long-lasting theoretical frameworks–
geocentrism and genocentrism–we discuss the different epistemological role played by …

We present a method that captures the fluctuations beyond mean field in chemical reactions
in the regime of small copy numbers and hence large fluctuations, using self-consistently …

Effective and robust regulation of biomolecular processes is crucial for designing reliable
synthetic bio-devices functioning in uncertain and constantly changing biological …

Biological experiments have verified that EIciRNAs (a class of circRNA) produced from pre‐
mRNA can regulate gene expression, but the effect of regulation remains unexplored. Here …

We study the problem of optimal syntax-guided synthesis of stochastic Chemical Reaction
Networks (CRNs) that plays a fundamental role in design automation of molecular devices …

Chemical reaction networks (CRNs) are a versatile language for describing the dynamical
behaviour of chemical kinetics, capable of modelling a variety of digital and analogue …

Cells can sense temporal changes of molecular signals, allowing them to predict
environmental variations and modulate their behavior. This paper elucidates biomolecular …

Cells can maintain their homeostasis in a noisy environment since their signaling pathways
can filter out noise somehow. Several network motifs have been proposed for biological …

Biological cells naturally exchange information for adapting to the environment, or even
influencing other cells. One of the latest frontiers of synthetic biology stands in engineering …