Improving translation of animal models of addiction and relapse by reverse translation
Critical features of human addiction are increasingly being incorporated into complementary
animal models, including escalation of drug intake, punished drug seeking and taking …
animal models, including escalation of drug intake, punished drug seeking and taking …
Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology
Motivation has been defined as the process that allows organisms to regulate their internal
and external environment, and control the probability, proximity and availability of stimuli. As …
and external environment, and control the probability, proximity and availability of stimuli. As …
Understanding addiction using animal models
Drug addiction is a neuropsychiatric disorder with grave personal consequences that has an
extraordinary global economic impact. Despite decades of research, the options available to …
extraordinary global economic impact. Despite decades of research, the options available to …
[LIBRO][B] Behavior analysis and learning: A biobehavioral approach
WD Pierce, CD Cheney - 2017 - taylorfrancis.com
Using a consistent Skinnerian perspective, Behavior Analysis and Learning: A
Biobehavioral Approach, Sixth Edition provides an advanced introduction to the principles of …
Biobehavioral Approach, Sixth Edition provides an advanced introduction to the principles of …
Increased number and activity of a lateral subpopulation of hypothalamic orexin/hypocretin neurons underlies the expression of an addicted state in rats
Background The orexin (hypocretin) system is important for reward-driven motivation but has
not been implicated in the expression of a multiphenotype addicted state. Methods Rats …
not been implicated in the expression of a multiphenotype addicted state. Methods Rats …
Differential roles of medial prefrontal subregions in the regulation of drug seeking
The prefrontal cortex plays an important role in sha** cognition and behavior. Many
studies have shown that medial prefrontal cortex (mPFC) plays a key role in seeking …
studies have shown that medial prefrontal cortex (mPFC) plays a key role in seeking …
Dopamine circuit mechanisms of addiction-like behaviors
Addiction is a complex disease that impacts millions of people around the world. Clinically,
addiction is formalized as substance use disorder (SUD), with three primary symptom …
addiction is formalized as substance use disorder (SUD), with three primary symptom …
Less is more: prolonged intermittent access cocaine self-administration produces incentive-sensitization and addiction-like behavior
Rationale Contemporary animal models of cocaine addiction focus on increasing the
amount of drug consumption to produce addiction-like behavior. However, another critical …
amount of drug consumption to produce addiction-like behavior. However, another critical …
[LIBRO][B] A decade of orexin/hypocretin and addiction: where are we now?
One decade ago, our laboratory provided the first direct evidence linking orexin/hypocretin
signaling with drug seeking by showing that activation of these neurons promotes …
signaling with drug seeking by showing that activation of these neurons promotes …
Pathways to the persistence of drug use despite its adverse consequences
The persistence of drug taking despite its adverse consequences plays a central role in the
presentation, diagnosis, and impacts of addiction. Eventual recognition and appraisal of …
presentation, diagnosis, and impacts of addiction. Eventual recognition and appraisal of …
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