[HTML][HTML] Cyanobacteria: promising biocatalysts for sustainable chemical production

CJ Knoot, J Ungerer, PP Wangikar… - Journal of Biological …, 2018 - Elsevier
Cyanobacteria are photosynthetic prokaryotes showing great promise as biocatalysts for the
direct conversion of CO 2 into fuels, chemicals, and other value-added products. Introduction …

Cyanobacterial metabolic engineering for biofuel and chemical production

NJ Oliver, CA Rabinovitch-Deere, AL Carroll… - Current opinion in …, 2016 - Elsevier
Highlights•Metabolic engineering of cyanobacteria for biofuel and bulk chemical
production.•Photoheterotrophic production is improving titers in light and dark …

Modular engineering for efficient photosynthetic biosynthesis of 1-butanol from CO 2 in cyanobacteria

X Liu, R Miao, P Lindberg, P Lindblad - Energy & Environmental …, 2019 - pubs.rsc.org
Cyanobacteria are photoautotrophic microorganisms which can be engineered to directly
convert CO2 and water into biofuels and chemicals via photosynthesis using sunlight as …

Evaluation of promoters and ribosome binding sites for biotechnological applications in the unicellular cyanobacterium Synechocystis sp. PCC 6803

E Englund, F Liang, P Lindberg - Scientific reports, 2016 - nature.com
For effective metabolic engineering, a toolbox of genetic components that enables
predictable control of gene expression is needed. Here we present a systematic study of …

Uncovering a miltiradiene biosynthetic gene cluster in the Lamiaceae reveals a dynamic evolutionary trajectory

AE Bryson, ER Lanier, KH Lau, JP Hamilton… - Nature …, 2023 - nature.com
The spatial organization of genes within plant genomes can drive evolution of specialized
metabolic pathways. Terpenoids are important specialized metabolites in plants with diverse …

Enhancement of poly-3-hydroxybutyrate production in Synechocystis sp. PCC 6803 by overexpression of its native biosynthetic genes

W Khetkorn, A Incharoensakdi, P Lindblad… - Bioresource …, 2016 - Elsevier
Synechocystis sp. PCC 6803 strains overexpressing pha genes were constructed and
characterized for poly-3-hydroxybutyrate (PHB) production. These pha overexpressing …

Enhanced limonene production in a fast-growing cyanobacterium through combinatorial metabolic engineering

PC Lin, F Zhang, HB Pakrasi - Metabolic Engineering Communications, 2021 - Elsevier
Terpenoids are a large and diverse group of natural products with commercial applications.
Microbial production of terpenes is considered as a feasible approach for the stable supply …

Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii

I Pateraki, J Andersen-Ranberg, NB Jensen… - Elife, 2017 - elifesciences.org
Forskolin is a unique structurally complex labdane-type diterpenoid used in the treatment of
glaucoma and heart failure based on its activity as a cyclic AMP booster. Commercial …

Engineering cyanobacteria for production of terpenoids

PC Lin, HB Pakrasi - Planta, 2019 - Springer
Main conclusion This review summarizes recent advances in cyanobacterial terpenoid
production. The challenges and opportunities of improving terpenoid production by …

Phototrophic production of heterologous diterpenoids and a hydroxy-functionalized derivative from Chlamydomonas reinhardtii

KJ Lauersen, J Wichmann, T Baier, SC Kampranis… - Metabolic …, 2018 - Elsevier
Photosynthetic microalgae harbor enormous potential as light-driven green-cell factories for
sustainable bio-production of a range of natural and heterologous products such as …