Cognitive Fitness: Harnessing the Strength of Exerkines for Aging and Metabolic Challenges

M Saheli, M Moshrefi, M Baghalishahi, A Mohkami… - Sports, 2024 - mdpi.com
Addressing cognitive impairment (CI) represents a significant global challenge in health and
social care. Evidence suggests that aging and metabolic disorders increase the risk of CI …

Lactate-induced autophagy activation: unraveling the therapeutic impact of high-intensity interval training on insulin resistance in type 2 diabetic rats

H Pirani, A Soltany, M Hossein Rezaei… - Scientific Reports, 2024 - nature.com
Impaired autophagy is a hallmark of diabetes. The current study proposed to investigate if
high intensity interval training (HIIT) induced lactate accumulation could stimulate autophagy …

Lung molecular and histological changes in type 2 diabetic rats and its improvement by high-intensity interval training

MA Rajizadeh, K Khoramipour, S Joukar… - BMC Pulmonary …, 2024 - Springer
Abstract Background Type 2 diabetes (T2D) leads to serious respiratory problems. This
study investigated the effectiveness of high-intensity interval training (HIIT) on T2D-induced …

High intensity interval training can ameliorate hypothalamic appetite regulation in male rats with type 2 diabetes: the role of Leptin

K Khoramipour, MH Rezaei, E Madadizadeh… - Cellular and Molecular …, 2023 - Springer
Disruption of leptin (LEP) signaling in the hypothalamus caused by type 2 diabetes (T2D)
can impair appetite regulation. The aim of this study was to investigate whether the …

Myrtenol inhalation mitigates asthma-induced cognitive impairments: an electrophysiological, behavioral, histological, and molecular study

K Esmaeilpour, E Jafari, F Rostamabadi… - Molecular …, 2024 - Springer
Asthma is an inflammatory disorder with significant health problems. It generally affects the
lungs but can also impact brain performance via several mechanisms. Some investigations …

Exercise training improves diabetic renal injury by reducing fetuin-A, oxidative stress and inflammation in type 2 diabetic rats

S Saberi, M Askaripour, M Khaksari, MA Rajizadeh… - Heliyon, 2024 - cell.com
Background Diabetic kidney disease (DKD) stands as a primary contributor to end-stage
renal disease, associated with heightened mortality in cardiovascular diseases. This study …

ATP releasing channels and the ameliorative effects of high intensity interval training on diabetic heart: a multifaceted analysis

S Joukar, MA Rajizadeh, MA Bejeshk, SS Alavi… - Scientific Reports, 2024 - nature.com
Abstract Type 2 diabetes (T2D) can cause severe cardiac complications at functional,
histologic and molecular levels. These pathological complications could be mediated by …

Systematic review and meta-analysis of the effects of exercise on cognitive impairment and neuroprotective mechanisms in diabetes mellitus animal models

Z Liu, H Huang, L Zhao - Metabolic Brain Disease, 2024 - Springer
This study aims to assess the effects of exercise on cognitive impairment behavioral
performance and neuroprotective mechanisms in diabetes mellitus (DM) animal models …

The Antiaging and Antioxidative Effects of a Combination of Resveratrol and High‐Intensity Interval Training on the Frontal Lobe in Aged Rats: The Role of SIRTS 4 …

A Mehrabi, R Nuori, A Gaeini… - Oxidative Medicine …, 2025 - Wiley Online Library
Introduction: High‐intensity interval training (HIIT) is a form of interval exercise that
enhances capacity and benefits well‐being. Resveratrol is a naturally occurring polyphenol …

Changes in the hippocampal level of tau but not beta-amyloid may mediate anxiety-like behavior improvement ensuing from exercise in diabetic female rats

K Khoramipour, MH Rezaei, A Moslemizadeh… - Behavioral and Brain …, 2024 - Springer
Background In the present study, we investigated the effect of high-intensity interval training
(HIIT) on cognitive behaviors in female rats with a high-fat diet+ streptozotocin (STZ) …