Targeted therapy in advanced non-small cell lung cancer: current advances and future trends
U Majeed, R Manochakian, Y Zhao, Y Lou - Journal of hematology & …, 2021 - Springer
Lung cancer remains the leading cause of cancer-related mortality in both men and women
in the US and worldwide. Non-small cell lung cancer is the most common variety accounting …
in the US and worldwide. Non-small cell lung cancer is the most common variety accounting …
Molecular mechanism (s) of regulation (s) of c-MET/HGF signaling in head and neck cancer
Head and neck cancer is the sixth most common cancer across the globe. This is generally
associated with tobacco and alcohol consumption. Cancer in the pharynx majorly arises …
associated with tobacco and alcohol consumption. Cancer in the pharynx majorly arises …
Drug resistance to targeted therapeutic strategies in non-small cell lung cancer
W Liu, Y Du, R Wen, M Yang, J Xu - Pharmacology & therapeutics, 2020 - Elsevier
Rapidly develo** molecular biology techniques have been employed to identify cancer
driver genes in specimens from patients with non-small cell lung cancer (NSCLC). Inhibitors …
driver genes in specimens from patients with non-small cell lung cancer (NSCLC). Inhibitors …
[HTML][HTML] MET exon 14 skip** mutations in non–small-cell lung cancer: an overview of biology, clinical outcomes, and testing considerations
In the United States, lung cancer is the second most frequently diagnosed type of cancer
and the leading cause of cancer deaths. 1 Non–small-cell lung cancer (NSCLC), which …
and the leading cause of cancer deaths. 1 Non–small-cell lung cancer (NSCLC), which …
Biomarker-targeted therapies in non–small cell lung cancer: current status and perspectives
H Guo, J Zhang, C Qin, H Yan, T Liu, H Hu, S Tang… - Cells, 2022 - mdpi.com
Non-small-cell lung cancer (NSCLC) is one of the most common malignancies and the
leading causes of cancer-related death worldwide. Despite many therapeutic advances in …
leading causes of cancer-related death worldwide. Despite many therapeutic advances in …
Utility of incorporating next-generation sequencing (NGS) in an Asian non-small cell lung cancer (NSCLC) population: Incremental yield of actionable alterations and …
AC Tan, GGY Lai, G San Tan, SY Poon, B Doble… - Lung Cancer, 2020 - Elsevier
Objectives There is an expanding list of therapeutically relevant biomarkers for non-small
cell lung cancer (NSCLC), and molecular profiling at diagnosis is paramount. Tissue attrition …
cell lung cancer (NSCLC), and molecular profiling at diagnosis is paramount. Tissue attrition …
Combinational blockade of MET and PD-L1 improves pancreatic cancer immunotherapeutic efficacy
E Li, X Huang, G Zhang, T Liang - Journal of Experimental & Clinical …, 2021 - Springer
Background Dysregulated expression and activation of receptor tyrosine kinases (RTKs) are
associated with a range of human cancers. However, current RTK-targeting strategies exert …
associated with a range of human cancers. However, current RTK-targeting strategies exert …
[HTML][HTML] Tyrosine kinase inhibitors
Tyrosine Kinase Inhibitors - StatPearls - NCBI Bookshelf US flag An official website of the
United States government Here's how you know NIH NLM Logo Access keys NCBI Homepage …
United States government Here's how you know NIH NLM Logo Access keys NCBI Homepage …
MET-targeted therapies and clinical outcomes: a systematic literature review
Y Dong, J Xu, B Sun, J Wang, Z Wang - Molecular Diagnosis & Therapy, 2022 - Springer
Introduction Numerous therapeutic agents specifically targeting the mesenchymal-epithelial
transition (MET) oncogene are being developed. Objective The aim of the current review …
transition (MET) oncogene are being developed. Objective The aim of the current review …
Therapeutic strategies in METex14 skip** mutated non-small cell lung cancer
LM Drusbosky, R Dawar, E Rodriguez… - Journal of Hematology & …, 2021 - Springer
METex14 skip** mutations occur in about 3–4% of lung adenocarcinoma patients and 1–
2% of patients with other lung cancer histology. The MET receptor tyrosine kinase and its …
2% of patients with other lung cancer histology. The MET receptor tyrosine kinase and its …