[HTML][HTML] ELF3, ELF5, EHF and SPDEF transcription factors in tissue homeostasis and cancer
The epithelium-specific ETS (ESE) transcription factors (ELF3, ELF5, EHF and SPDEF) are
defined by their highly conserved ETS DNA binding domain and predominant epithelial …
defined by their highly conserved ETS DNA binding domain and predominant epithelial …
The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy
A cancer cell-centric view has long dominated the field of cancer biology. Research efforts
have focussed on aberrant cancer cell signalling pathways and on changes to cancer cell …
have focussed on aberrant cancer cell signalling pathways and on changes to cancer cell …
ETS transcription factors as emerging drug targets in cancer
The ETS family of proteins consists of 28 transcription factors, many of which have been
implicated in development and progression of a variety of cancers. While one family …
implicated in development and progression of a variety of cancers. While one family …
Bone morphogenetic proteins in breast cancer: dual role in tumourigenesis?
EL Alarmo, A Kallioniemi - Endocrine-related cancer, 2010 - erc.bioscientifica.com
A cancer cell-centric view has long dominated the field of cancer biology. Research efforts
have focussed on aberrant cancer cell signalling pathways and on changes to cancer cell …
have focussed on aberrant cancer cell signalling pathways and on changes to cancer cell …
ELF5 drives angiogenesis suppression though stabilizing WDTC1 in renal cell carcinoma
T Li, L Xu, Z Wei, S Zhang, X Liu, Y Yang, Y Gu… - Molecular Cancer, 2023 - Springer
Background Renal cell carcinoma (RCC) is a common malignant tumor of the urinary
system. Angiogenesis is a main contributing factor for tumorigenesis. E74-like transcription …
system. Angiogenesis is a main contributing factor for tumorigenesis. E74-like transcription …
ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19
Despite two years of intense global research activity, host genetic factors that predispose to
a poorer prognosis of COVID-19 infection remain poorly understood. Here, we prioritise …
a poorer prognosis of COVID-19 infection remain poorly understood. Here, we prioritise …
Sparse semiparametric canonical correlation analysis for data of mixed types
Canonical correlation analysis investigates linear relationships between two sets of
variables, but it often works poorly on modern datasets because of high dimensionality and …
variables, but it often works poorly on modern datasets because of high dimensionality and …
ETV7 reduces inflammatory responses in breast cancer cells by repressing the TNFR1/NF-κB axis
The transcription factor ETV7 is an oncoprotein that is up-regulated in all breast cancer (BC)
types. We have recently demonstrated that ETV7 promoted breast cancer progression by …
types. We have recently demonstrated that ETV7 promoted breast cancer progression by …
ETV7 regulates breast cancer stem-like cell features by repressing IFN-response genes
Cancer stem cells (CSCs) represent a population of cells within the tumor able to drive
tumorigenesis and known to be highly resistant to conventional chemotherapy and …
tumorigenesis and known to be highly resistant to conventional chemotherapy and …
Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1
X Li, S Li, B Li, Y Li, S Aman, K **a, Y Yang… - NPJ Precision …, 2021 - nature.com
E74-like ETS transcription factor 5 (ELF5) is involved in a wide spectrum of biological
processes, eg, mammogenesis and tumor progression. We have identified a list of p300 …
processes, eg, mammogenesis and tumor progression. We have identified a list of p300 …