Radiomics is the extraction of predefined mathematic features from medical images for
predicting variables of clinical interest. Recent research has demonstrated that radiomics …

The advent of immunotherapy, a groundbreaking advancement in cancer treatment, has
given rise to the prominence of the tumor microenvironment (TME) as a critical area of …

Background It is unknown whether the additional information provided by multiparametric
dual-energy CT (DECT) could improve the noninvasive diagnosis of the aggressive …

Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the third leading
cause of cancer‐related death worldwide. HCC exhibits strong inter‐tumor heterogeneity …

As a solid tumor with high glycolytic activity, hepatocellular carcinoma (HCC) produces
excess lactic acid and increases extracellular acidity, thus forming a unique …

Liver cancer is a major global health concern, ranking among the top causes of cancer-
related deaths worldwide. Despite advances in medical research, the prognosis for liver …

Identifying the relationship between imaging features and genetic variation (a term coined
“imaging genomics”) offers valuable insight into the pathogenesis of cancer, as well as …

With the increasing demand for precision medicine in cancer patients, radiogenomics
emerges as a promising frontier. Radiogenomics is originally defined as a methodology for …

Background Even after curative resection, the prognosis for patients with intrahepatic
cholangiocarcinoma (iCCA) remains disappointing due to the extremely high incidence of …

Abstract Background Proliferative hepatocellular carcinomas (HCCs) is a class of
aggressive tumors with poor prognosis. We aimed to construct a computed tomography (CT) …