Antifungal activity of thiosemicarbazones, bis (thiosemicarbazones), and their metal complexes

K Bajaj, RM Buchanan, CA Grapperhaus - Journal of Inorganic …, 2021 - Elsevier
Fungi are ubiquitous in nature, and typically cause little or no environmental or pathogenic
damage to their plant, animal, and human hosts. However, a small but growing number of …

Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis

AS Nagle, S Khare, AB Kumar, F Supek… - Chemical …, 2014 - ACS Publications
Leishmaniasis is a parasitic disease that presents four main clinical syndromes: cutaneous
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …

The emerging role of microRNAs in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection

R Mirzaei, F Mahdavi, F Badrzadeh… - International …, 2021 - Elsevier
The novel coronavirus disease 2019 (COVID-19) pandemic has imposed significant public
health problems for the human populations worldwide after the 1918 influenza A virus …

1H NMR-based Metabolomic Profiling in Mice Infected with Mycobacterium tuberculosis

JH Shin, JY Yang, BY Jeon, YJ Yoon… - Journal of proteome …, 2011 - ACS Publications
Tuberculosis (TB) is one of three major infectious diseases, and the control of TB is
becoming more difficult because of the emergence of multidrug-resistant and extensively …

Environmental and occupational factors associated with leptospirosis: a systematic review

M Baharom, N Ahmad, R Hod, MH Ja'afar, FS Arsad… - Heliyon, 2024 - cell.com
Background Leptospirosis is a neglected emerging zoonotic disease with a profound public
health impact worldwide with higher burden of disease in resource-poor countries. The …

Biochemistry and medicinal chemistry of the dengue virus protease

C Nitsche, S Holloway, T Schirmeister… - Chemical …, 2014 - ACS Publications
Dengue virus is the pathogenic principle behind several medical conditions. The most
common disease caused by this virus is dengue fever, characterized by high fever and flu …

Fruitful decade for antileishmanial compounds from 2002 to late 2011

H Hussain, A Al-Harrasi, A Al-Rawahi, IR Green… - Chemical …, 2014 - ACS Publications
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …

High-fat diet induces dynamic metabolic alterations in multiple biological matrices of rats

Y An, W Xu, H Li, H Lei, L Zhang, F Hao… - Journal of proteome …, 2013 - ACS Publications
Obesity is a condition resulting from the interactions of individual biology and environmental
factors causing multiple complications. To understand the system's metabolic changes …

A content analysis of newspaper coverage of COVID-19 pandemic for develo** a pandemic management framework

NM Zafri, S Afroj, IM Nafi, MMU Hasan - Heliyon, 2021 - cell.com
Background The emergence of COVID-19 pandemic has not only shaken the global health
sector, but also almost every other sector, including economic and education sectors …

Binding of low molecular weight inhibitors promotes large conformational changes in the dengue virus NS2B-NS3 protease: fold analysis by pseudocontact shifts

L de la Cruz, THD Nguyen, K Ozawa… - Journal of the …, 2011 - ACS Publications
The two-component dengue virus NS2B-NS3 protease (DEN NS2B-NS3pro) is an
established drug target, but inhibitor design is hampered by the lack of a crystal structure of …