Rapid diagnosis is one key pillar to end tuberculosis (TB). Point-of-care tests (POCTs)
facilitate early detection, immediate treatment, and reduced transmission of TB disease. This …

Rapid, accurate, sputum-free tests for tuberculosis (TB) triage and confirmation are urgently
needed to close the widening diagnostic gap. We summarise key technologies and review …

Early cancer detection greatly increases the chances for successful treatment, but available
diagnostics for some tumours, including lung adenocarcinoma (LA), are limited. An ideal …

Many proteins are present at low concentrations in biological samples, and therefore,
techniques for ultrasensitive protein detection are necessary. To overcome challenges with …

A major challenge in many clinical diagnostic applications is the measurement of low-
abundance proteins and other biomolecules in biological fluids. Digital technologies such as …

Single-molecule counting is the most accurate and precise method for determining the
concentration of a biomarker in solution and is leading to the emergence of digital diagnostic …

Detecting diseases at the molecular level aids in early diagnosis and treatment. However,
traditional immunological detection techniques, such as enzyme-linked immunosorbent …

More humans have died of tuberculosis (TB) than any other infectious disease and millions
still die each year. Experts advocate for blood-based, serum protein biomarkers to help …

BACKGROUND Tuberculosis (TB) kills more people than any other infection, and new
diagnostic tests to identify active cases are required. We aimed to discover and verify novel …

Introduction There is an urgent medical need to differentiate active tuberculosis (ATB) from
latent tuberculosis infection (LTBI) and prevent undertreatment and overtreatment. The aim …