Molecular mechanisms underlying cyclophosphamide-induced cognitive impairment and strategies for neuroprotection in preclinical models
KM Ibrahim, SF Darwish, EM Mantawy… - Molecular and Cellular …, 2024 - Springer
Cyclophosphamide has drastically enhanced the expectancy and quality of life of cancer
patients. However, it is accompanied by diverse neurological complications which are …
patients. However, it is accompanied by diverse neurological complications which are …
Morinda lucida Benth (Rubiaceae): A review of its ethnomedicine, phytochemistry and pharmacology
KE Adewole, AF Attah, JO Adebayo - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnomedicinal relevance Natural products derived from plants have served the primary
healthcare needs of millions of indigenous people for centuries, many of which have been …
healthcare needs of millions of indigenous people for centuries, many of which have been …
[HTML][HTML] Phytochemical profiling and neuroprotective activity of Callistemon subulatus leaves against cyclophosphamide-induced chemobrain
O Rabie, HAS El-Nashar, MY George… - Biomedicine & …, 2023 - Elsevier
Cyclophosphamide (CPA) is a chemotherapeutic drug used for various types of cancers.
However, patients receiving CPA for long periods suffer cognitive impairment associated …
However, patients receiving CPA for long periods suffer cognitive impairment associated …
Nerolidol ameliorates cyclophosphamide-induced oxidative stress, neuroinflammation and cognitive dysfunction: plausible role of Nrf2 and NF-κB
Aim Cyclophosphamide (CP) is a potent anticancer and immunosuppressant drug. Studies
have shown significant oxidative stress and cognitive impairment but neuroinflammatory and …
have shown significant oxidative stress and cognitive impairment but neuroinflammatory and …
Antidiabetic drug sitagliptin blocks cyclophosphamide cerebral neurotoxicity by activating Nrf2 and suppressing redox cycle imbalance, inflammatory iNOS/NO/NF-κB …
AC Famurewa, NT Asogwa, SC Ezea - International Immunopharmacology, 2023 - Elsevier
Cyclophosphamide (CYP) is a classic DNA-interacting anticancer agent with broad
application in chemotherapy. However, CYP cerebral neurotoxicity is a worrisome side effect …
application in chemotherapy. However, CYP cerebral neurotoxicity is a worrisome side effect …
Neuroprotective potential of ferulic acid against cyclophosphamide‐induced neuroinflammation and behavioral changes
T Mishra, K Nagarajan, PK Dixit… - Journal of Food …, 2022 - Wiley Online Library
In the present study, ferulic acid (FRA) has been explored for possible neuroprotective
effects against cyclophosphamide (CP)‐induced neurotoxicity in the Swiss Albino mice …
effects against cyclophosphamide (CP)‐induced neurotoxicity in the Swiss Albino mice …
Biflavonoid quercetin protects against cyclophosphamide–induced organ toxicities via modulation of inflammatory cytokines, brain neurotransmitters, and astrocyte …
AY Onaolapo, FO Ojo, OJ Onaolapo - Food and chemical toxicology, 2023 - Elsevier
Background Cyclophosphamide use has been associated with increased oxidative stress in
cells and tissues. Quercetin's antioxidative properties make it of potential benefit in such …
cells and tissues. Quercetin's antioxidative properties make it of potential benefit in such …
The protective effects of spirulina in cyclophosphamide induced nephrotoxicity and urotoxicity in rats
O Sinanoglu, AN Yener, S Ekici, A Midi, FB Aksungar - Urology, 2012 - Elsevier
OBJECTIVE: To evaluate the role of Spirulina, a blue-green algae with antioxidant
properties in the protection of cyclophosphamide-induced nephrotoxicity and hemorrhagic …
properties in the protection of cyclophosphamide-induced nephrotoxicity and hemorrhagic …
Quercetin attenuates cyclophosphamide induced‐immunosuppressive indoleamine 2, 3‐dioxygenase in the hippocampus and cerebral cortex of male Wister rats
AP Ebokaiwe, OR Ushang, TH Ogunwa… - … of Biochemical and …, 2022 - Wiley Online Library
This study investigated the protective effect of quercetin against cyclophosphamide‐induced
immunosuppressive indoleamine 2, 3‐dioxygenase (IDO) via the mechanism of oxidative …
immunosuppressive indoleamine 2, 3‐dioxygenase (IDO) via the mechanism of oxidative …
[PDF][PDF] Phytochemistry and mode of action of some tropical spices in the management of type-2 diabetes and hypertension
SA Adefegha, G Oboh - African Journal of Pharmacy and …, 2013 - researchgate.net
Spices are important food supplements and/or food products, which have been used as
flavouring agents and preservatives for thousands of years in tropical Africa, Asia and other …
flavouring agents and preservatives for thousands of years in tropical Africa, Asia and other …